Microporous structure blood vessel stent

A technology of vascular stents and microporous structures, which is applied in the direction of blood vessels, stents, and human tubular structures, and can solve problems such as stenosis, limited drug loading, and uncontrollable drug release rates.

Inactive Publication Date: 2005-12-21
SOUTHEAST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the existing drug-coated stents are drug-coated on the surface of ordinary bare stents. The stent design does not fully consider the characteristics of drug loading, so its structure has uncontrollable drug release rate. At the same time, because the stent-coated surface can only cover 5-12% of the intimal surface of the blood vessel, so its drug loading is limited, and about 10% of restenosis occurs

Method used

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  • Microporous structure blood vessel stent
  • Microporous structure blood vessel stent
  • Microporous structure blood vessel stent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] Embodiment one: see Figure 5 As shown, a microporous vascular stent is composed of metal microtubes carved into a network structure by laser. The network management structure is composed of 8 sets of support rings 10 connected by connecting curved rods. Each set of support rings 10 is composed of 6 unit waves 11. The arc section 18 of the offset pass is formed, and there are 3 connecting curved bars between adjacent supporting rings 10. The connecting curved bars are straight section micro-holes 21, and the connecting curved bars are evenly arranged along the circumferential direction.

Embodiment 2

[0026] Embodiment two: see Figure 6 As shown, a microporous vascular stent is composed of metal microtubes carved into a network structure by laser. The network management structure is composed of 10 sets of support rings 10 connected by connecting curved rods. Each set of support rings 10 is composed of 8 unit waves 11. The circular arc segment 15 is formed, and there are 4 connecting curved rods between adjacent supporting rings 10. The connecting curved rods are arc segment micro-holes 22, and the connecting curved rods are evenly arranged along the circumferential direction.

[0027] Carve the microporous structure on the support rods and connecting curved rods of the stent, and secondly, make the material near the micropores without reducing the mechanical properties of the material, and this structure will not deform the micropores when the stent is crimped or expanded, so it does not affect the micropores. impact on the contents contained within. It is beneficial to ...

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Abstract

The present invention relates to a blood vessel support with micro pore structure. It has a reticular structure made of metal micro tube graven by laser, and the described reticular structure is characterized by that it is formed from several groups of micro pore supporting rings which are connected by means of micro pore connection curved bars, the described every group of micro pore supporting rings is formed from 4-16 unit waves, and adjacent two micro pore supporting rings are connected by adopting 2-16 micro pore connection curved bars, and the described unit wave is formed from flat straight part and curved part. Said micro pore structure support can be favorable for loading medicine, can raise medicine-loaded quantity; and is easy to control and release.

Description

technical field [0001] The invention relates to an expandable vascular stent for percutaneous puncture angioplasty to treat vascular obstruction. It specifically relates to a microporous vascular support combined with a microporous support ring and a microporous connecting curved rod, which belongs to the technical field of medical device manufacturing. Background technique [0002] After successful percutaneous transluminal coronary angioplasty (PTCA), 30% to 50% of restenosis still occurs within 3 to 6 months, and the occurrence of restenosis has become the field of minimally invasive interventional treatment of cardiovascular diseases Interesting research hotspots. [0003] With the deepening of research on the mechanism of restenosis, it is found that the three main causes of restenosis are smooth muscle cell proliferation, thrombus formation and vessel wall remodeling caused by minimally invasive interventional therapy. Maintaining local high drug concentration and lo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/91
CPCA61F2250/0068
Inventor 倪中华顾兴中易红汤文成王跃轩
Owner SOUTHEAST UNIV
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