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Medicine for treating gastric cavity pains, process for preparing the same and application thereof

A technology for epigastric pain and drugs, which is applied in the direction of drug combinations, pharmaceutical formulas, and medical preparations containing active ingredients, etc. It can solve the problems of difficult retention, difficult extraction and retention of active ingredients, etc., to achieve fewer components and maintain natural characteristics , the effect of not easy to decompose and destroy

Inactive Publication Date: 2006-02-15
SHENZHEN DONGFANG TAIGE BIOPHARML
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, pure traditional Chinese medicine preparations are used in the treatment of stomach cold pain mainly caused by epigastric pain. The most common methods are water decoction and water extraction and alcohol precipitation. It is difficult to retain the volatile parts or water-soluble parts of the active ingredients, that is to say, it is difficult to extract and retain the active ingredients in the raw materials to the greatest extent

Method used

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  • Medicine for treating gastric cavity pains, process for preparing the same and application thereof
  • Medicine for treating gastric cavity pains, process for preparing the same and application thereof
  • Medicine for treating gastric cavity pains, process for preparing the same and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The preparation of embodiment 1 drug soft capsule

[0039] Wash 0.8kg of dried ginger and 2.4kg of galangal with clean water, then dry at 50°C, pulverize the dried ginger and galangal to 20 mesh fine powder, and grind the dried ginger powder and galangal Ginger powder is combined with the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 45°C, the extraction pressure is 30mPa, and the extraction time is 2 hours; supercritical extraction The final medicinal residues are extracted by alcohol extraction and water precipitation method to extract hydrophilic effective active substances, the ethanol concentration is 75%, and the alcohol extraction temperature is 80°C. Concentrate the alcohol extract to a relative density of 1.2 (at 80°C), add 5.5 times the amount of water, stir well, let stand for 5 hours, filter, take the precipitate and d...

Embodiment 2

[0040] The preparation of embodiment 2 drug soft capsules

[0041] Wash 1.92kg of dried ginger and 1.28kg of galangal with clean water respectively, dry the dried ginger and galangal at 40°C respectively, grind the dried ginger and galangal into 20-day fine powder, and grind the The dried ginger powder and galangal powder combined and adopted the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 50°C, the extraction pressure is 26mPa, and the extraction time is 2.2 hours; the medicinal dregs after supercritical extraction are extracted with alcohol extraction and water precipitation method to extract effective hydrophilic active substances, the ethanol concentration is 80%, and the alcohol extraction temperature is 70°C; the alcohol extract is concentrated to a relative density of 1.1 (80°C), Add 6 times the amount of water and stir well, le...

Embodiment 3

[0042] The preparation of embodiment 3 drug soft capsules

[0043] Wash 1.6kg of dried ginger and 1.6kg of galangal with clean water respectively, dry the dried ginger and galangal at 60°C respectively, grind the dried ginger and galangal into 20-mesh fine powder, and grind the The dried ginger powder and galangal powder combined and adopted the supercritical carbon dioxide fluid extraction device of 100ml-SPE manufactured by Hanwei (HANDWAY) company to extract lipophilic effective active substances. The extraction temperature is 47°C, the extraction pressure is 25mPa, and the extraction time is 1.9 hours; the medicinal dregs after supercritical extraction are extracted by alcohol extraction and water precipitation method, the effective hydrophilic active substance is extracted, the ethanol concentration is 75%, and the alcohol extraction temperature is 75°C. Concentrate the alcohol extract to a relative density of 1.0 (80°C), add 5 times the amount of water and stir well, let...

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Abstract

The invention relates to a pharmaceutical composition for treating gastric cavity pains and process for preparation, wherein the composition comprises dried ginger extract 10-70% and galangal rhizome extract 30-90%.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a medicine for treating epigastric pain, and the invention also relates to a preparation method and application of the medicine. Background technique [0002] With the advent of modern society, the pace of life is becoming more and more tense, and the number of gastrointestinal diseases with epigastric pain as the main symptom is also increasing significantly. Drugs with definite analgesic effect, easy to take, no toxic side effects or few side effects are more popular among people. demand. Western medicine treatment of epigastric pain is mainly symptomatic treatment, and gastrointestinal antispasmodic drugs are mostly used to relieve pain. Although the pain relief effect is rapid and reliable, it often brings more adverse reactions and side effects to patients. It can be a temporary solution but not a permanent cure. [0003] The traditional Chinese medicine has acc...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/48A61P1/14
Inventor 蔡健聪
Owner SHENZHEN DONGFANG TAIGE BIOPHARML
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