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Tissue micro-array chip arranged according to biological behavior of tumor

A tissue microarray and biological technology, applied in the biological field, can solve problems such as difficult to adapt to the academic requirements of research, large demand for tissue samples, and large experimental workload.

Inactive Publication Date: 2006-04-05
SHANG OUTDO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The research method of traditional tissue technology is difficult to adapt to the academic requirements of the research due to the large amount of tissue samples required and the heavy experimental workload.

Method used

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  • Tissue micro-array chip arranged according to biological behavior of tumor
  • Tissue micro-array chip arranged according to biological behavior of tumor
  • Tissue micro-array chip arranged according to biological behavior of tumor

Examples

Experimental program
Comparison scheme
Effect test

example 1

[0012] Example 1 Primary liver cancer biological behavior tissue chip

[0013] Primary liver cancer is one of the common malignant tumors in my country. The mortality rate is high, ranking third only to the stomach and esophagus in the order of malignant tumor deaths. This tissue chip arranges primary liver cancer tissues with different biological behaviors on a glass slide to make a tissue chip with high throughput and high research value. Product renderings such as figure 2 shown. Primary liver cancer can be divided into three types according to histological type: hepatocellular carcinoma, cholangiocarcinoma and mixed liver carcinoma. Now combine Table 1 to illustrate the specific composition of the primary liver cancer biological behavior tissue chip: ①There is a carbon core marking point on the upper left of the tissue chip to indicate the reading direction of the tissue chip; ②Column 1-1, 1- The two columns are composed of primary liver cancers with different degrees...

example 2

[0015] Example 2 Esophageal Cancer Biological Behavior Tissue Chip

[0016] Esophageal cancer is one of the common malignant tumors in my country. The mortality rate is high, ranking second only to the stomach in the order of malignant tumor deaths. This tissue chip arranges esophageal cancer tissues with different biological behaviors on a glass slide to make a tissue chip with high throughput and high research value. Product renderings such as image 3shown. Esophageal cancer can be divided into squamous cell carcinoma of the esophagus, adenoid cystic carcinoma of the esophagus adenocarcinoma, mucinous adenocarcinoma of the esophagus, tubular adenocarcinoma of the esophagus adenocarcinoma, small cell carcinoma of the esophagus, and adenosquamous carcinoma of the esophagus according to histological types. Now combine with Table 2 to illustrate the specific composition of the tissue chip for the biological behavior of esophageal cancer: ① There is a carbon core marking poin...

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Abstract

The invention discloses an organizing micro array chip which comprises sheet bases and organizing points, wherein the organizing points are arranged and attached on the sheet bases by girding type; the organizing points are arranged in line by one or some biology and behavior character.

Description

1. Technical field [0001] The invention belongs to the field of biotechnology, and more specifically relates to a tissue chip fixed on a sheet base. 2. Background technology [0002] With the development of histology and pathology, people's understanding of the human body or other animals and plants has developed from the anatomical organ level to the tissue and cell level. However, since the complete organ is difficult to observe with a microscope, it is necessary to cut the organ into very thin sections for staining and observation. In order to solve this problem, histological techniques have emerged. The principle of this method is to cut the organ into small pieces of tissue, fix it with formalin, use alcohol to remove the moisture in the tissue, then immerse it in xylene or benzene solution to remove the alcohol, and finally immerse the tissue piece in molten paraffin solution Remove the xylene from the medium, put it into the mold and embed it with paraffin solution, ...

Claims

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Application Information

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IPC IPC(8): G01N33/48
Inventor 郜恒骏张宝峰
Owner SHANG OUTDO BIOTECH CO LTD
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