Novel 2-oxo-heterocyclic compounds and the pharmaceutical compositions comprising the same

A compound, oxo technology, applied in physical therapy, organic chemistry, massage auxiliary products, etc., can solve the problems of side effects, limit the use of conventional drugs, can not achieve satisfactory results, and achieve the effect of strong inhibitory activity
CN1791579AInactive Publication Date: 2006-06-21KOREA RES INST OF BIOSCI & BIOTECH
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Patent Information

Authority / Receiving Office
CN · China
Current Assignee / Owner
KOREA RES INST OF BIOSCI & BIOTECH
Publication Date
2006-06-21
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to novel 2-oxo-cyclic compounds, processes for their preparation and pharmaceutical compositions containing said compounds. The present invention provides a pharmaceutical composition for the prevention and treatment of inflammatory diseases, including pain or inflammation caused by rheumatic diseases, for example, rheumatoid arthritis, juvenile spondyloarthropathy, gout, osteoarthritis, systemic Lupus erythematosus and juvenile arthritis and inflammatory syndromes, eg due to myositis, gingivitis, synovitis, ankylosing spondylitis, burstitis, burns and scars, inflammatory Crohn's disease, type I diabetes. Thus, it can be used as a therapeutic method in the treatment and prevention of inflammatory diseases.
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Description

technical field

[0001] The present invention relates to novel 2-oxo-heterocyclic compounds which are effective anti-inflammatory agents and pharmaceutical compositions comprising said compounds. Background technique

[0002] Inflammation due to mechanical scars or various bacterial infections etc. is a normal reaction of the human body related to edema, pain etc. Usually, arthritic syndrome occurs only temporarily, but, when severe, it can cause long-term and eventual deformity. Joint disease can be divided into several groups of diseases, such as rheumatoid arthritis (RA), rheumatic inflammation associated with the disease, etc. Of these, specifically, arthritis is the most frequent and is a chronic disease characterized by inflammatory changes in the synovial lining of the joint capsule, which may progress to affect all joints of the body, at worst will cause disability. Progressive joint diseases such as rheumatoid arthritis cause joint disorders such as joint deformit...

Claims

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