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Ointment for treating female genital system inflammation and its preparing process

A reproductive system and ointment technology, applied in the field of traditional Chinese medicine preparations, can solve the problems of short retention time in the vagina, poor mucous membrane adhesion, suppository melting and easy flow out, etc., so as to prolong the retention time and improve the curative effect

Inactive Publication Date: 2006-10-04
GUIYANG XINTIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Uterine erosion, infectious vaginitis, trichomonas vaginitis, etc. see the above syndromes. Currently, traditional Chinese medicine suppositories with good curative effect on the market have the following disadvantages: the suppository melts and flows out easily when used, and the residence time in the vagina is short. , poor mucoadhesion, foreign body sensation and discomfort, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] Take Phellodendron 100g, Sophora flavescens 100g, Catechin 100g, Dry alum 80g, Borneol 20g, Catechin and dry alum are crushed through a 120 mesh sieve, and set aside; Borneol is dissolved in 29g ethanol, Set aside; Treat Phellodendron, Sophora flavescens add 6, 5, Decoct with 5 times the amount of water three times, 2 hours for the first time, 1 hour for the second and third times, combine the decoction, filter, concentrate the filtrate to an extract with a relative density of 1.05-1.10 (60-70°C), add ethanol Make the ethanol content in the solution be 75%, let it stand for 12 hours, take the supernatant to reclaim the ethanol, and concentrate it into an extract whose relative density is 1.15 (70°C), and set aside; 550g polyethylene glycol 400, 100g polyethylene glycol Glycol 4000, 80g glycerin heating and melting, add 1g ethylparaben and stir to dissolve in turn, stir and dissolve catechin powder, then sprinkle dry alum powder and stir evenly, add the above alcohol imme...

Embodiment 2

[0028] Take Phellodendron 100g, Sophora flavescens 100g, Catechin 100g, Dry alum 80g, Borneol 20g, Catechin and dry alum are crushed through a 120 mesh sieve, and set aside; Borneol is dissolved in 29g ethanol, Set aside; Treat Phellodendron, Sophora flavescens add 6, 5, Decoct with 5 times the amount of water three times, 2 hours for the first time, 1 hour for the second and third times, combine the decoction, filter, concentrate the filtrate to an extract with a relative density of 1.05-1.10 (60-70°C), add ethanol Make the ethanol content in the solution be 75%, let it stand for 12 hours, take the supernatant to reclaim the ethanol, and concentrate it into an extract whose relative density is 1.15 (70°C), and set aside; 500g polyethylene glycol 400, 150g polyethylene glycol Glycol 4000, 80g glycerin heating and melting, add 1g ethylparaben and stir to dissolve in turn, stir and dissolve catechin powder, then sprinkle dry alum powder and stir evenly, add the above alcohol imme...

Embodiment 3

[0030] Take Phellodendron 100g, Sophora flavescens 100g, Catechin 100g, Dry alum 80g, Borneol 20g, Catechin and dry alum are crushed through a 120 mesh sieve, and set aside; Borneol is dissolved in 29g ethanol, Set aside; Treat Phellodendron, Sophora flavescens add 6, 5, Decoct with 5 times the amount of water three times, 2 hours for the first time, 1 hour for the second and third times, combine the decoction, filter, concentrate the filtrate to an extract with a relative density of 1.05-1.10 (60-70°C), add ethanol Make the ethanol content in the solution be 75%, let it stand for 12 hours, take the supernatant to reclaim the ethanol, and concentrate it into an extract whose relative density is 1.15 (70°C), and set aside; 500g polyethylene glycol 400, 130g polyethylene glycol Glycol 4000, 100g glycerin, heat and melt, add 0.1g ethylparaben and stir to dissolve, catechin powder stir to dissolve, then sprinkle dry alum powder and stir evenly, add the above alcohol immersion paste...

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PUM

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Abstract

The invention relates to an ointment for treating inflammation of reproductive system and process for preparation, wherein the ointment is prepared from corktree bark, flavescent sophora root, black catechu, dried alum, boneol, black catechu and dried alum through ethanol dissolving, watering and boiling three times, merging the grilling liquid, filtering, concentrating the filtrate into grease, charging alcosol and stewing 12 hours, reclaiming ethanol from the supernatant fluid, condensating into concrete, charging polyethylene glycol 400, polyethylene glycol 4000 and glycerin, heating till melting, stirring and dissolving, charging catechu powder, stirring to dissolve, charging the alcohol, stirring to 40 deg C, charging baras camphor, stirring into grease form, loading and packaging.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine prescription preparations, and specifically relates to an ointment for treating female reproductive system inflammation, and also relates to a preparation method thereof. Background technique [0002] Cervical erosion, infectious vaginitis, trichomonal vaginitis and other female vaginitis diseases are the most common gynecological diseases. At present, it is used for clearing away heat and dampness, detoxifying and anti-inflammatory, removing putrefaction and promoting granulation. Uterine erosion, infectious vaginitis, trichomonas vaginitis, etc. see the above syndromes. Currently, traditional Chinese medicine suppositories with good curative effect on the market have the following disadvantages: the suppository melts and flows out easily when used, and the residence time in the vagina is short. , Poor mucoadhesion, foreign body sensation and discomfort. Contents of the invention ...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/06A61P15/00A61K33/06A61K31/045
Inventor 董大伦
Owner GUIYANG XINTIAN PHARMA CO LTD
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