Medicament for treating rheumatism

A rheumatism and medicine box technology, applied in the field of medicine boxes for treating rheumatism, can solve the problems of large adverse reactions, small adverse reactions, inconvenient use, etc., so as to improve medication dependence, ensure medication course of treatment, and reduce desensitization. effect of effect

Inactive Publication Date: 2006-12-27
HUNAN ZHENGQING PHARM GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Although the sinomenine hydrochloride preparation has the characteristics of both first-line and second-line antirheumatic drugs, less side effects, and high safety, neither tablet nor injection alone can give full play to its advantages
Because tablets and injections have different characteristics, among them, injections have fast onset of action, strong analgesic and anti-inflammatory effects, and can be administered locally or systemically through various routes; but they are not convenient enough to use for a long time, and the adverse reactions are relatively large
Tablets (sustained-release tablets, enteric-coated tablets) are easy to use, have stable effects, relatively small adverse reactions, and can be used for a long time; but the onset of action is slow, the effect is relatively weak, and the symptoms of acute or severe patients cannot be quickly relieved

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] The preparation specifications are 250 sinomenine hydrochloride injections containing 12 mg of sinomenine hydrochloride per 1 ml; 480 sinomenine hydrochloride enteric-coated tablets containing 20 mg of sinomenine hydrochloride per tablet are prepared; 25 injections and tablets 48 tablets of the drug are divided into push-in packaging to make 10 drug boxes.

Embodiment 2

[0014] The preparation specifications are 240 sinomenine hydrochloride injections containing 14 mg of sinomenine hydrochloride per 1 ml; 160 sinomenine hydrochloride sustained-release tablets containing 60 mg of sinomenine hydrochloride are prepared; 24 injections and tablets 16 tablets are packed in push packs to make 10 kits.

Embodiment 3

[0016] The preparation specifications are 230 sinomenine hydrochloride injections containing 16 mg of sinomenine hydrochloride per 1 ml; 240 sinomenine hydrochloride sustained-release tablets containing 60 mg of sinomenine hydrochloride per tablet are prepared; 23 injections and tablets 24 tablets of the drug are packed in push-in packaging to make 10 drug boxes.

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PUM

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Abstract

The invention discloses a medicinal kit for treating rheumatic diseases, wherein the medicinal kit comprises 12-72 units of tuduranine hydrochloride tablets containing effective dosage and 5-25 units of tuduranine hydrochloride injections containing 12-40mg tuduranine hydrochloride per ml.

Description

technical field [0001] The invention relates to a medicine, in particular to a medicine box for treating rheumatism. Background technique [0002] Sinomenine hydrochloride preparations have been developed and marketed for more than 10 years, and three generations of products have been developed. The first-generation product is sinomenine hydrochloride tablets (enteric-coated tablets), and its indication is rheumatic diseases; the second-generation products are sinomenine hydrochloride tablets and sinomenine hydrochloride injection, of which sinomenine hydrochloride tablets have Two types of indications for rheumatic diseases and chronic nephritis; the third-generation product is sinomenine hydrochloride sustained-release tablets. [0003] Although the sinomenine hydrochloride preparation has the characteristics of both first-line and second-line antirheumatic drugs, few side effects, and high safety, it cannot give full play to the advantages of single-use tablets or inject...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4748A61K9/20A61K9/08A61P29/00
Inventor 吴飞驰仇萍易建峰
Owner HUNAN ZHENGQING PHARM GRP CO LTD
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