Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor

A technology of tissue samples and boxes, applied in the field of holders for operating and embedding tissue samples for pathological analysis, boxes for embedding and subsequent slicing, which can solve the problems of increasing human errors

Active Publication Date: 2007-01-17
BIOPATH AUTOMATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This multiple manual manipulation and repeated tissue processing increases the possibility of human error and requires specially trained skilled histological technicians to ensure that the tissue samples finally bonded to glass slides and analyzed by pathologists have the Best state and orientation for accurate diagnosis

Method used

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  • Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
  • Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor
  • Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor

Examples

Experimental program
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Embodiment Construction

[0026] Box structure / type detection

[0027]Referring to Figures 1 and 2, the cassette 10 may be used in an automated embedding device, such as the one disclosed in the aforementioned incorporated PCT Application No. PCT / US02 / 30779. More specifically, the device can utilize an optoelectronic identification feature that can use a robotic system to determine which of at least two types of boxes 10 is being removed from an input cage. Different types of cassettes 10 may be, for example, of different sizes or have other different features and / or functions. Multiple interrogation points allow the use of an optical scanner to assign a binary signal to each interrogation point on the cassette 10 , which may be the holes 12 in the flange 14 located around the cassette body 16 . Since at this point it is beneficial for all cassettes 10 to use the same embedding frame, all cassettes 10 are designed to fit into the frame with a similar up-down orientation. As additional box features ar...

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PUM

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Abstract

A cassette (10) for holding a tissue sample includes a body having a bottom wall (28) and a plurality of side walls (26) extending upwardly with respect to the bottom wall to define an interior space for receiving the tissue sample. A lid (24) is configured to be received in the interior space, and the cassette (10) is sectionable in a microtome. Sensing elements (12) are associated with the body (16) or lid (24) and configured to allow an automated sensing system to determine at least one characteristic of the cassette (10). A flange (14) extends along upper portions of at least two of the side walls (26) and includes a plurality of holes (12, 20). Other features are included to more effectively and efficiently manufacture and use the cassette (10).

Description

[0001] related application [0002] This application claims priority to U.S. Patent Application No. 60 / 512,147, filed October 17, 2003, and is related to PCT Application Nos. PCT / US02 / 30779 and PCT / US02 / 30775, which are still pending and disclose all The contents are incorporated into this application by reference. technical field [0003] The present invention relates generally to scaffolds for manipulating and embedding tissue samples for pathological analysis, and more particularly to scaffolds capable of receiving one or more tissue samples and capable of being embedded and subsequently processed with one or more tissue samples Sliced ​​boxes. Background technique [0004] To accurately diagnose a wide variety of tissue diseases and conditions, medical professionals must remove one or more tissue samples from a patient. This process of taking tissue from the body is called a biopsy. When one or more tissue samples are taken and sent to a pathology laboratory, in order...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01L3/00G01N1/31
CPCG01N1/31B01L2300/022G01N2001/315B01L3/545
Inventor 沃伦·P·威廉森四世托马斯·J·沃德斯蒂芬·P·惠特拉奇
Owner BIOPATH AUTOMATION
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