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Method and Devices for Cardiac Radiofrequency Catheter Ablation

Inactive Publication Date: 2007-03-01
MUSC FOUND FOR RES DEV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Benefits of technology

[0005] Embodiments of the invention comprise methods for computing convection cooling parameters associated with the site for the application of RF ablation. Additional embodiments of the invention comprise devices for the control of cardiac RF ablation. Further embodiments of the invention comprise computer readable medium capable of execution in a computer or other processing unit whereby an ablation lesion size is predicted based upon the input of certain parameters or measurements. Parame

Problems solved by technology

If the temperature at the electrode-tissue interface reaches about 100° C., coagulated plasma and desiccated tissue may form on the electrode, preventing effective delivery of the current, predisposing the patient to thromboembolic complications, and necessitating the removal of the catheter so that the coagulated material can be wiped off the electrode.
Conversely, the site of origin of an arrhythmia that has not been successfully ablated may later become permanently nonfunctional if it is within the border zone of a lesion and if microvascular injury and inflammation within this zone result in progressive necrosis.

Method used

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  • Method and Devices for Cardiac Radiofrequency Catheter Ablation
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  • Method and Devices for Cardiac Radiofrequency Catheter Ablation

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Embodiment Construction

[0019] Cardiac radiofrequency (RF) catheter ablation has become the treatment of choice for a wide array of both supraventricular and ventricular arrhythmia. The dimensions of the lesion created during RF ablation depend on several factors such as catheter geometry, catheter-endocardial contact, and blood flow. Several studies examined the dependence of lesion size on blood flow [1-4]. Convective cooling by the blood carries away heat from the catheter tip and endocardium, enabling deposition of more RF energy deeper into the tissue. When RF power is not limited, higher blood flow can result in wider and deeper RF lesions. These results have been shown in ex vivo experiments [1, 3] and computer models [4, 5]. Similarly, in vivo experiments in a porcine animal model have shown that ablation site within the heart affects lesion size. Mukherjee, et al., classified different ablation sites in the endocardium according to flow conditions (low / medium / high), and found significant differenc...

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Abstract

Embodiments of the invention comprise methods and devices that allow quantification of blood convective cooling at the cardiac RF catheter ablation site and allow for prediction of lesion size and / or computation of RF energy parameters and characteristics.

Description

CROSS REFERENCE TO RELATED APPLICATIONS [0001] The application claims the benefit of Provisional Patent Application entitled “Quantification of Local Convectional Cooling During Cardiac Radiofrequency Catheter Ablation”, by Haemmerich and Saul, Ser. No. 60 / 711,742 filed on Aug. 26, 2005, and hereby incorporated by reference as if rewritten in full.BACKGROUND OF THE INVENTION [0002] Radiofrequency (RF) ablation is a medical procedure which can be used to treat some types of rapid heart beating including conditions such as supraventricular tachyarrhythmias. Ablation can be used to treat a wide variety of tachycardias, which can involve heart tissues in the upper chambers (atria), also called supraventricular, or the lower chambers (ventricles), called ventricular tachycardias (SVT or VT). In some cases, a small number of cells (a “focus”) start firing rapidly and ablation can eliminate the focus. In other types of tachycardia, an electrical circuit exists within which the electrical s...

Claims

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Application Information

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IPC IPC(8): A61B18/18
CPCA61B18/02A61B18/1206A61B18/1492A61B2018/0212A61B2018/00702A61B2018/00791A61B2018/00351
Inventor HAEMMERICH, DIETERSAUL, J. PHILIP
Owner MUSC FOUND FOR RES DEV