Global motion invariant signatures for fast and accurate motion tracking in a digital image-based elasto-tomography system

a technology of global motion and invariant signatures, applied in mammography, medical science, diagnostics, etc., can solve the problems of requiring radiation exposure, significant patient discomfort, and significant health problems of breast cancer, and achieve accurate and efficient tracking of large numbers of markers, significant freedom in the amount of pixel movement, and improved accuracy

Inactive Publication Date: 2008-11-20
BOUNDARY LIFESCI LTD
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Benefits of technology

[0013]The invention has the advantages of accurately and efficiently tracking large numbers of markers that are close together for a large array of digital cameras. The invention has flexibility in varying the type of pattern and

Problems solved by technology

Breast cancer is a significant health problem in both developed and developing countries.
However mammography can cause significant patient discomfort and requires radiation exposure.
Furthermore there are often variable results and inconsistencies in reading and interpreting the images of breast tissue from th

Method used

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  • Global motion invariant signatures for fast and accurate motion tracking in a digital image-based elasto-tomography system
  • Global motion invariant signatures for fast and accurate motion tracking in a digital image-based elasto-tomography system
  • Global motion invariant signatures for fast and accurate motion tracking in a digital image-based elasto-tomography system

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[0031]There are many different methods in the literature for registering images [Jan Modersitzki (2004), “Numerical Methods for Image Registration”, Oxford University Press, New York]. These methods are usually either feature or intensity based. Intensity based methods avoid the feature extraction stage but work on whole intensity images so are computationally demanding. In the context of the DIET system as shown in FIGS. 1A and 1B, to capture the full motion of the breast surface with very fine detail requires a large array of high resolution cameras and potentially 1000's of frames for each camera to be analyzed to capture small subtle variations in the breast surface due to a small tumour. Thus methods that work with whole intensity images, for example Normalized Cross-Correlation (NCC) based [J. P. Lewis (1995), “Fast Normalized Cross-Correlation”, Vision Interface, 120-1231 are not feasible for the DIET system.

[0032]Feature based methods are potentially suitable since they mini...

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Abstract

A method for converting digital images of an actuated breast into an accurate description of breast surface motion from a digital image-based elasto-tomography system comprises the steps of artificially placing a high density of fiducial markers on the breast surface, whereby the fiducial markers have different qualities and are placed in different proportions according to their quality; utilizing motion invariant properties of the fiducial markers to form a global motion invariant signature; tracking the markers on the actuated breast surface from image to image in each digital camera using the global motion invariant signature; and using the cameras calibration to measure the breast surface motion.

Description

FIELD OF THE INVENTION[0001]The invention relates generally to the field of breast cancer screening, and in particular to a technique of breast surface motion tracking in a digital image-based elasto-tomography system.BACKGROUND OF THE INVENTION[0002]Breast cancer is a significant health problem in both developed and developing countries. It is estimated that each year the disease is diagnosed in over 1,000,000 women worldwide and is the cause of death in over 400,000 women. There are many treatment options available, including surgery, chemotherapy, radiation therapy, and hormonal therapy. These treatments are significantly more effective in reducing the mortality of the disease with early detection through breast cancer screening programmes.[0003]The standard method for detection of breast cancer is mammography. However mammography can cause significant patient discomfort and requires radiation exposure. Furthermore there are often variable results and inconsistencies in reading a...

Claims

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Application Information

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IPC IPC(8): A61B6/00
CPCA61B5/0048A61B5/0091A61B5/4312A61B5/0051
Inventor CHASE, JAMES GEOFFREYHANN, CHRISTOPHER ERICRAY, LAWRENCE ALLEN
Owner BOUNDARY LIFESCI LTD
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