Composition comprising an extract of hardy kiwi for preventing or treating baldness disorders or seborrheic skin disorders

Abstract

Provided is a use of a crude extract, non-polar solvent soluble extract or purified extract of the hardy kiwifruit for the preparation of therapeutic agent for treating and preventing baldness disorder and seborrheic skin disease in human and mammal, and health care food, food additives, feed additives, cosmetic composition comprising the same. The hardy kiwifruit reduced blood DHT level, promoted the formation of hair root in mouse model experiment, and inhibited the falling out of hair and improved seborrheic skin disease of volunteers such as keratigenous skin, seborrhea etc.

Description

[0001]This application is a continuation application of U.S. application Ser. No. 12 / 868,130 (now allowed) filed on Aug. 25, 2010, which is a continuation-in-part application of U.S. application Ser. No. 11 / 573,445 filed on Feb. 8, 2007, which is a national stage application under 35 U.S.C. §371 of PCT / KR2004 / 002010 filed on Aug. 10, 2004, the disclosures of which are incorporated herein by reference.BACKGROUND OF THE INVENTION[0002]1. Technical Field[0003]The present invention relates to a composition comprising an extract of hardy kiwi having preventing, improving or treating activity of baldness disorder or seborrheic skin disease.[0004]2. Background Art[0005]The present invention relates to a composition comprising the extract of hardy kiwi having ability of preventing and treating on baldness disease or seborrheic skin disease, and especially, a composition comprising a crude extract, non-polar solvent soluble extract, or purified fraction of hardy kiwi extract for the preventi...

AI Technical Summary

Benefits of technology

This patent describes the use of a crude extract, non-polar solvent soluble extract or purified extract of hardy kiwi to make a therapeutic agent for treating or preventing baldness and seborrheic skin disease in humans or mammals. The researchers tested the extract in mouse models and found that it reduced blood DHT levels, formed more hair roots, and inhibited the falling out of hair and improved seborrheic skin disease. The extract can be formulated as a pharmaceutical with acceptable carriers and additives, and can be used in child and infant food or as a cosmetic additive to prevent, improve, or treat been frequently used and safe.

Problems solved by technology

Finasteride, an oral 5-α-reductase inhibitor, is available in the market, however it has several disadvantages such as recurrence at cease of administration, usage limitation in pregnant women, and sexual dysfunction upon long-term administration; minoxidil has been used to treat male pattern baldness combined with other agents such as cell division accelerator, vasodilator, capillary formation promotor, immuno-suppressor, cAMP modulator, EGF (epithelial cell growth factor), and cell proliferation modulator.

However it also has adverse effects such as repetitive recurrence and rapid reduction of blood pressure at cease of administration too.

However it also has several disadvantages including recurrence and adverse effects upon long term administration.

Most of them do not provide enough efficacy to accomplish a satisfactory activity and have several disadvantages including recurrence and adverse effects.

However, the hair growing effect of the above described composition disclosed therein have not been fully supported or identified in any of the disclosure.

However, there has been not reported or disclosed an activity of an extract of hardy kiwi for treating or preventing alopecia and seborrheic skin disease in any of above literatures.

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