Method of predicting a blood dilution risk value

Abstract

The present invention provides for a clinical decision support system which makes use of a numerical model which dynamically describes a blood dilution of a blood circulation. Based on measured coagulation data and maybe other patient information, loss of hemostatic balance is predicted based on calculations of certain protein concentrations. Additionally, a calculation arrangement translates at least some of the calculated values of concentrations of human blood proteins into a risk value which risk value describes a risk of clotting and / or embolism and / or bleeding. A time development of that risk value is displayed to the user.

Description

FIELD OF THE INVENTION[0001]The present invention relates to clinical decision support systems. In detail, the present invention relates to a method of predicting a blood dilution risk value of a first blood circulation, to a clinical decision support system for predicting and displaying a blood dilution risk value, a program element for predicting and displaying a blood dilution risk value and a computer readable medium.BACKGROUND OF THE INVENTION[0002]Patients who undergo surgery experience blood loss and lowered concentrations of blood clotting proteins due to reactions of the hemostatic system to the surgical cuts. Apart from this, the patient's clotting system may be inhibited by Heparin-like compounds to prevent embolism. The blood loss and lowering of coagulation protein concentrations is countered by transfusions of blood plasma, IV fluids, protein substitution solutions etc. The challenge of maintaining a safe hemostatic balance in a patient undergoing surgery is a very dif...

AI Technical Summary

Benefits of technology

[0006]There may be a need to analyze blood loss and lowered concentrations of blood clotting proteins and provide accurate countermeasures before the analyzed blood circulation is out of balance. Furthermore, there may be a need to provide a user with the information when the countermeasures have to be stopped and to provide the user with said information before the hemostatic balance of the analyzed blood circulation starts to tip in the other direction.

[0016]Furthermore, the term “hemostatic situation” may be understood to be used synonymously to a blood dilution state of the blood circulation. In other words the herein presented numerical model enables a user to calculate and predict the present and future blood dilution states of the analyzed blood circulation and translates the latter into a risk value, i.e. a blood dilution risk value.

[0023]Such a predicted dangerous state of dilution may be displayed to the user by the calculated and predicted blood dilution risk value, which was generated by the model based on the calculated and predicted blood protein concentrations. Furthermore, the method may comprise to calculate the correspondingly expected effect of each available countermeasure. The solution may be offered to a user by a graphical user interface which interface may be linked to a hospital information system. Therefore, the presented method provides for a continuous estimation of the patients stability, and if desired, an alarm when the patient threatens to become unstable and may suggest for the optimal countermeasure.

Problems solved by technology

The challenge of maintaining a safe hemostatic balance in a patient undergoing surgery is a very difficult one, and multiple strategies exist to meet this challenge.

A downside to the way of working as described above is that countermeasures are only taken when the patient is already out of balance, and stopped only when the hemostatic balance starts to tip in the other direction.

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