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Multiple Chamber, Expandable Therapeutic Agent Delivery Device

a technology of therapeutic agent and delivery device, which is applied in the direction of multi-lumen catheter, balloon catheter, surgery, etc., can solve the problems of drawbacks of drug eluting balloon and direct injection devi

Active Publication Date: 2015-06-18
MIRIZZI MICHAEL S
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Benefits of technology

The patent is about a device and method for delivering therapeutic agents to the internal surfaces of a body lumen or cavity. The device includes an expandable balloon structure with multiple chambers for carrying the therapeutic agent. The device can be used in procedures such as treatment of atherosclerotic plaque in the arterial vasculature and injection of sclerosing agents into blood vessels. The patent describes the drawbacks of existing methods and devices for such procedures and proposes an improved method and device for treating the vascular system and other body lumens.

Problems solved by technology

Both the drug eluting balloon and the direct injection devices have drawbacks.
Few devices and method have been developed for improving the administration of liquid medical substances, such as sclerosing agents, into the veins or other body lumens.

Method used

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  • Multiple Chamber, Expandable Therapeutic Agent Delivery Device
  • Multiple Chamber, Expandable Therapeutic Agent Delivery Device
  • Multiple Chamber, Expandable Therapeutic Agent Delivery Device

Examples

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Embodiment Construction

[0037]In various embodiments, systems and methods are provided herein for treating blood vessels, bodily lumens, body cavities, or other structures by direct application of a therapeutic agent to an interior wall of such structures. In some embodiments, such therapeutic agent delivery may be performed with a therapeutic agent delivery device having multiple chambers. Embodiments of such devices may employ very simple construction while providing substantial flexibility and diversity in performing clinical procedures. Various embodiments and examples of such devices are shown and described with reference to the accompanying drawings and figures. References made to particular examples and implementations are for illustrative purposes, and are not intended to limit the scope of the invention or the claims.

[0038]Some embodiments provide a multi-chamber therapeutic agent delivery device that is capable of simultaneously excluding blood from the target vessel and delivering an effective q...

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Abstract

A device having multiple chambers may be configured to expand to contact a substantial section of an interior wall of a body structure or lumen in order to simultaneously exclude blood or other liquid from a target structure while providing for delivery of a therapeutic agent directly to the interior wall. The expandable device may be manufactured from a plurality of flat sheets of material heat sealed to one another to form an inflation chamber and one, two or more delivery chambers. The sheets may also be bonded to an elongate catheter body having inflation and delivery lumens. The excluding of blood flow and delivery of therapeutic agents are completed by the same device.

Description

CROSS-REFERENCE TO RELATED APPLICATION[0001]This application claims the benefit of and takes priority from U.S. App. No. 61 / 915,134 filed on Dec. 12, 2013, the contents of which are hereby incorporated by reference.FIELD OF THE INVENTION[0002]This invention generally relates to therapeutic agent delivery devices, and more particularly to devices for targeted delivery of therapeutic agents to an internal surface of a body lumen or cavity.BACKGROUND OF THE INVENTION[0003]Several minimally-invasive medical interventional procedures make use of inflatable balloon structures to apply treatments to targeted areas within a body lumen. Such balloons are typically formed by bonding an extruded tubular material to an inflation or delivery lumen. Examples of procedures that may use such balloons include treatment of atherosclerotic plaque in the arterial vasculature, and delivery of therapeutic agents, such as sclerosants, into blood vessels for treatment of venous reflux or other conditions.[...

Claims

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Application Information

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Patent Type & Authority Applications(United States)
IPC IPC(8): A61M25/10A61M25/00
CPCA61M25/1002A61M25/003A61M2025/105A61M2210/12A61M2025/1075A61M2025/1086A61M2025/0031A61M2025/1072A61M25/1029
Inventor MIRIZZI, MICHAEL S.
Owner MIRIZZI MICHAEL S