7-oh-cannabidiol (7-oh-cbd) and/or 7-oh-cannabidivarin (7-oh-cbdv) for use in the treatment of epilepsy

a technology of cannabis and cannabinoids, which is applied in the field of 7ohcannabinoids (7ohcbd) and/or 7ohcannabinoids (7ohcbdv) for use in the treatment of epilepsy, can solve the problems of difficult treatment, cognitive, behavioral and motor delays, and inability to obtain seizure freedom
US20170209390A1Inactive Publication Date: 2017-07-27GW RES LTD
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Patent Information

Authority / Receiving Office
US · United States
Patent Type
Applications(United States)
Current Assignee / Owner
GW RES LTD
Publication Date
2017-07-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The present invention relates to the use of 7-hydroxy-cannabidol (7-OH-CBD) and / or 7-hydroxy-cannabidivarin (7-OH-CBDV) in the treatment of epilepsy. Preferably the cannabinoid metabolites are isolated from plants to produce a highly purified extract or can be reproduced synthetically.
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Description

[0001] The present invention relates to the use of 7-hydroxy-cannabidol (7-OH-CBD) and / or 7-hydroxy-cannabidivarin (7-OH-CBDV) in the treatment of epilepsy.

[0002] Preferably the cannabinoid metabolites are isolated from plants to produce a highly purified extract or can be reproduced synthetically.BACKGROUND TO THE INVENTION

[0003] Epilepsy occurs in approximately 1% of the population worldwide, (Thurman et al., 2011) of which 70% are able to adequately control their symptoms with the available existing anti-epileptic drugs (AED). However, 30% of this patient group, (Eadie et al., 2012), are unable to obtain seizure freedom from the AED that are available and as such are termed as suffering from “treatment-resistant epilepsy” (TRE).

[0004] There are several different types of AED available to treat epilepsy, some of the most common AED defined by their mechanisms of action are described in the following tables:Examples of Narrow Spectrum AED

[0005] Narrow-spectrum AEDMechanismPhenytoinSodiu...

Claims

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