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5 results about "Immunomodulin" patented technology

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CD86 Variant Immunomodulatory Proteins and Uses Thereof

PendingUS20260193313A1DiseaseImmunomodulations

Provided herein are variant CD86 polypeptides, immunomodulatory proteins comprising variant CD86 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.

CD86 Variant Immunomodulatory Proteins and Uses Thereof

CD86 Variant Immunomodulatory Proteins and Uses Thereof

CD86 Variant Immunomodulatory Proteins and Uses Thereof

Owner:ALPINE IMMUNE SCIENCES INC

April and baff inhibitory immunomodulatory proteins and methods of use thereof

PendingCN122277700ADiseaseTransmembrane activator and CAML interactor

This invention relates to APRIL and BAFF inhibitory immunomodulatory proteins and methods of using them, specifically providing immunomodulatory proteins exhibiting neutralizing activity against BAFF and APRIL (or BAFF / APRIL heterotrimers). The immunomodulatory proteins provided herein include variant domains of transmembrane activators and CAML interactors (TACI). The provided immunomodulatory proteins include TACI-Fc fusion proteins. Nucleic acid molecules encoding said immunomodulatory proteins are also provided. The immunomodulatory proteins provide therapeutic efficacy against a variety of immune diseases, disorders, or conditions. Compositions and methods for preparing and using such proteins are also provided.

April and baff inhibitory immunomodulatory proteins and methods of use thereof

Owner:ALPINE IMMUNE SCIENCES INC

CD80 variant immunomodulatory proteins and uses thereof

PendingAU2023203586B2CD80Immunomodulations

Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.

CD80 variant immunomodulatory proteins and uses thereof

CD80 variant immunomodulatory proteins and uses thereof

CD80 variant immunomodulatory proteins and uses thereof

Owner:ALPINE IMMUNE SCIENCES INC

CD80 variant immunomodulatory proteins and uses thereof

ActiveUS12668634B2DiseaseCD80

Provided herein are variant CD80 polypeptides, immunomodulatory proteins comprising variant CD80 polypeptides, and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided.

CD80 variant immunomodulatory proteins and uses thereof

CD80 variant immunomodulatory proteins and uses thereof

CD80 variant immunomodulatory proteins and uses thereof

Owner:ALPINE IMMUNE SCIENCES INC

Immunomodulatory proteins of the ICOS ligand variant and uses thereof

ActiveDE602017095787T2Cell receptors/surface-antigens/surface-determinantsImmunomodulationsImmunomodulin

Owner:ALPINE IMMUNE SCIENCES INC

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