The invention is applicable to the technical field of grain reserve and provides a grain unloading depot dust removal system. The system comprises a grain unloading depot and a feeding port formed inthe grain unloading depot, an inlet and an outlet are formed in the grain unloading depot, a plurality of dust removal devices are arranged in the grain unloading depot, the dust removal devices and the inlet and the outlet are located on the same side, and gear pieces are movably arranged at the positions, corresponding to the inlet and the outlet, of the grain unloading depot. The dust removal devices and the inlet and outlet are located on the same side, so that the trend of wind is converged to the dust removal devices, the consistency of the wind direction is guaranteed, airflow turbulence in the grain unloading warehouse is avoided, and the dust removal effect is improved, a gear piece is arranged at the inlet / outlet, therefore, the inlet and the outlet can be sealed through the blocking pieces, the grain unloading depot is in a sealed state as a whole, the situation that dust removal is affected by natural wind due to the fact that the grain unloading depot is opened in the dustremoval process is avoided, it is further guaranteed that the wind direction is consistent, it is guaranteed that materials do not raise dust everywhere in the unloading process, and the dust removaleffect is greatly improved.