The invention discloses a special compound fertilizer for watermelons and a preparation method of the special compound fertilizer. The special compound fertilizer for watermelons comprises the following substances in parts by weight: 10-26 parts of high-quality candy pomace, 2-4 parts of fulvic acid, 1-4 parts of adhesive, 10-28 parts of urea, 8-20 parts of monoammonium phosphate, 2-15 parts of potassium sulfate, 20-30 parts of ammonium sulfate, 1-4 parts of trace elements, 2-5 parts of charcoal and 3-5 parts of traditional Chinese medicine. The preparation method comprises the following steps: grinding the previous substances, uniformly mixing, and granulating, thereby obtaining the special compound fertilizer for watermelons. The special compound fertilizer for watermelons disclosed by the invention has the quick effect of an inorganic fertilizer and also has the long-acting and slow-release effects of an organic fertilizer, the volume weight of the soil is reduced, the granular structure in the soil is increased, the pH value of the soil is regulated, the special compound fertilizer has the effects of effectively expelling insects and sterilizing, the sugar content of the watermelon fruits is improved, and the solid content is increased, so that the yield and quality of the watermelons are improved. Meanwhile, the orchard soil can be improved, the environment is protected, and the special compound fertilizer has wide application prospects in green fruit production.