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Traditional Chinese medicinal composition for treating insomnia and its preparing process

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for treating insomnia and its preparation, can solve the problems of poor drug effect and rough preparation process, and achieve non-addiction, elimination of conditioned avoidance reflex, and outstanding selection characteristics Effect

Inactive Publication Date: 2007-11-28
刘小野
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, because most of them are large compound prescriptions, the preparation process is relatively rough, and the drug effect is obviously inferior to that of stable drugs.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] The preferred embodiment is made from the following raw materials:

[0030] 15 grams of Moutan bark, 10 grams of Shichangpu, 12 grams of Sophora flavescens, and 12 grams of Cyperus cyperi.

[0031] Preparation:

[0032] (1) Pulverize the Cortex Moutan, soak for 8 hours, distill for 4 hours, collect the distillate, refrigerate and filter, dry the sediment, and collect the medicinal liquid after distillation;

[0033] (2) Pulverize Shichangpu, Sophora flavescens and Rhizoma Cyperi, soak in 340 grams of water for 2 hours, distill for 2 hours, then distill with 272 water for 1 hour, collect volatile oil while distilling;

[0034] (3) Combine the extracts obtained in step (1) and step (2), and concentrate to a relative density of 1.10, where the relative density is at a temperature of 60°C;

[0035] (4) add ethanol alcohol precipitation to the concentrated solution obtained in step (3) to reach 70% ethanol, and filter after standing for 8 hours, and the obtained filtrate r...

Embodiment 2

[0039] The preferred embodiment is made from the following raw materials:

[0040] 6 grams of Moutan bark, 20 grams of Shichangpu, 3 grams of Sophora flavescens, and 12 grams of Cyperus cyperi.

[0041] Preparation:

[0042] (1) Pulverize the Cortex Moutan, soak for 8 hours, distill for 3 hours, collect the distillate and refrigerate and filter, dry the sediment, and collect the medicinal liquid after distillation;

[0043] (2) Pulverize Shichangpu, Sophora flavescens and Rhizoma Cyperi, soak in 340 grams of water for 2 hours, distill for 2 hours, then distill with 272 water for 1 hour, collect volatile oil while distilling;

[0044] (3) Combine the extracts obtained in step (1) and step (2), and concentrate to a relative density of 1.10, where the relative density is at a temperature of 60°C;

[0045] (4) add ethanol alcohol precipitation to the concentrated solution obtained in step (3) to reach 70% ethanol, and filter after standing for 8 hours, and the obtained filtrate ...

Embodiment 3

[0049] The preferred embodiment is made from the following raw materials:

[0050] Moutan bark 12 grams, Shichangpu 5 grams, Sophora flavescens 20 grams, Cyperus cyperus 6 grams.

[0051] Various methods:

[0052] (1) Pulverize the Cortex Moutan, soak for 8 hours, distill for 5 hours, refrigerate and filter after collecting the distillate, dry the precipitate, and collect the medicinal liquid after distillation;

[0053] (2) Pulverize Acorus flavescens, flavescens, and Rhizoma Cyperi, soak in 310 grams of water for 2 hours, distill for 2 hours, then distill with 248 water for 1 hour, and collect volatile oil while distilling;

[0054] (3) Combine the extracts obtained in step (1) and step (2), and concentrate to a relative density of 1.10, where the relative density is at a temperature of 60°C;

[0055](4) add ethanol alcohol precipitation to the concentrated solution obtained in step (3) to reach 70% ethanol, and filter after standing for 8 hours, and the obtained filtrate ...

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PUM

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Abstract

The invention relates to a traditional Chinese medicinal composition for treating insomnia and its preparing process, wherein the composition is prepared from the following raw materials (by weight portion), bark of peony root 6-20, acorus gramineus soland 5-20, kuh-seng 3-20, nutgrass flatsedge rhizome 6-20, and the preparing process comprises the follwing steps: (1) disintegrating bark of peony root, immersing and distilling, (2) disintegrating, immersing and distilling grassleaved sweetflag rhizome, flavescent sophora root and nutgrass flatsedge rhizome twice and collecting volatile oil, (3) combining and concentrating the raffinates obtained in step (1) and (2), charging ethanol for depositing, filtering, reclaiming ethanol and concentrating, spray drying the condensation liquid, obtaining concrete powder for later use, mixing the dried precipitate obtained in step (1) with the volatile oil obtained in step (2), charging beta cyclodextrin, coating with grinding method, charging beta-cyclodextrin and mixing homogeneously, finally packing capsules.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating insomnia and a preparation method thereof. Background technique [0002] With the continuous acceleration of the pace of real life and work, the tremendous pressure brought about by economic transformation, and the pressure brought by various examinations to candidates, etc., make people's spirits continue to be in a state of high tension and overload. The number of people with neurasthenia caused by mental stress is increasing day by day, and insomnia has become a disease that seriously affects the quality of life of many patients and has become a prominent public health problem. [0003] For the treatment of insomnia, Western medicine mostly uses anti-anxiety drugs, such as diazepam, clonazepam, alprazolam, sultazepam and so on. The efficacy of these drugs is definite. However, long-term use of the drug will cause drug resistance. In order to achieve the curative effec...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8905A61K36/888A61K36/71A61K36/489A61K9/48A61P25/20
Inventor 刘小野
Owner 刘小野