Astragalus root dripping pill and its preparing method

A technology of astragalus root and dripping pills, which is applied in the directions of pill delivery, pharmaceutical formulations, and medical preparations containing active ingredients, etc., can solve problems such as being unfavorable to improve patients' ability to seek medical treatment, bioavailability of liver and intestine first-pass effect, and adverse overall health level, etc. , to achieve the effect of benefiting labor protection and environmental protection, improving bioavailability, and drug safety

Inactive Publication Date: 2009-06-24
牙克石市森健药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
The drug content of granules is also low, and it is inconvenient to take
[0008] In addition, conventional oral dosage forms, such as tablets, capsules, granules (infusions), etc., due to the granulation process in the preparation process, will generate relatively large dust pollution, which will cause health problems to the staff to a certain extent. harm, and also cause some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Huangqi dripping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of Astragalus extract: take an appropriate amount of Astragalus in g or kg, add water to decoct twice, the first time for 3 hours, the second time for 2 hours, combine the decoction, filter, and concentrate the filtrate to a relative density of about It is a thick paste of 1.3-1.4, or it can be dried continuously and crushed into dry powder to obtain it;

[0032] 2. Substrate: polyethylene glycol (2000.4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac;

[0033] 3. Proportion: with g or kg as the unit, by weight, astragalus extract: substrate = 1:1~1:9;

[0034] 4. Prepare according to the process given in [Preparatio...

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PUM

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Abstract

The present invention relates to a kind of medicine composition, astragalus dripping pill, with the functions of invigorating vital energy, consolidating superficial resistance, promoting diuresis, eliminating toxic matter and promoting granulation. The astragalus dripping pill is used in treating hard breath, heart palpitation, collapse, spontaneous perspiration, etc. The present invention has high bioavailability, fast medicine release, fast acting, high effective content, taking convenience and low cost, and its production process has no pollution. The astragalus dripping pill is prepared with astragalus root and medicine carrier as matrix.

Description

technical field [0001] The present invention relates to a kind of tonifying qi and consolidating the surface, diuretic, detoxification and expulsion of pus, and promoting granulation. A pharmaceutical composition for the treatment of ulcers, sores that have not healed for a long time, and particularly relates to an oral preparation of a pharmaceutical composition prepared from Astragalus membranaceus. Background technique [0002] Astragalus granule prepared according to the preparation method given in the ministerial drug standard WS3-B-2224-96 is a kind of granule that has the functions of invigorating qi and solidifying the surface, diuresis, detoxification and pus discharge, and muscle regeneration. It is used for shortness of breath and heart palpitations. Oral granules for the treatment of prostration, spontaneous sweating, body deficiency and edema, chronic nephritis; chronic diarrhea, prolapse of the anus, uterine prolapse, carbuncle and ulceration, and sores that do...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/481A61K9/20A61P13/12A61P1/14A61P1/12
Inventor 曲韵智
Owner 牙克石市森健药业有限公司
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