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American falx extract, medicinal composition containing it and its making method

A technology of Periplaneta americana and its extract, applied in the field of medicine, can solve the problems such as the preparation method of Kangfuxin liquid that has not been reported

Active Publication Date: 2009-08-12
SICHUAN GOODDOCTOR PANXI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Above-mentioned documents all do not report the preparation method of Kangfuxin Liquid (Periplaneta americana extract)

Method used

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  • American falx extract, medicinal composition containing it and its making method
  • American falx extract, medicinal composition containing it and its making method
  • American falx extract, medicinal composition containing it and its making method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 Preparation of Periplaneta americana Ethanol Extract

[0024] Coarsely crush 1000kg of dried Periplaneta americana, add 4 times the amount of 70% ethanol, soak for 1 hour, and extract twice at a temperature of 70°C for 8 hours for the first time; add 3 times the amount of ethanol for the second time, extract for 6 hours and combine Secondary extract, filter, when the filtrate is concentrated to a clear paste with a relative density of 1.09-1.16 (70°C), add water, keep stirring at 70°C for 60 minutes, let stand for 12 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, Recover ethanol from the filtrate, concentrate under reduced pressure to a liquid medicine (70°C) with a relative density of 1.16 to 1.22, add 50ml of glycerin for every 1000ml, stir well, filter, boil the filtrate for 30 minutes, divide into bottles, and then pass through 125°C, The pressure is 0.1Mpa, sterilized for 30 minutes, cooled to room temperature, that i...

Embodiment 2

[0025] Example 2 Preparation of Periplaneta americana Ethanol Extract

[0026] Coarsely crush 1000kg of dried Periplaneta americana, add 400kg of water for every 100kg of coarse powder, soak for 1 hour, the temperature is about 70°C, extract three times, the first time is 8 hours; add water 300kg for the second time, extract for 6 hours; third time Add water 300kg at a time and extract for 4 hours. Combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.10-1.20 (70°C), add 95% ethanol, keep stirring at 70°C for 30 minutes, let stand for 12 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, Recover ethanol from the filtrate, concentrate under reduced pressure to a relative density of 1.20-1.25 (70°C), add purified water and glycerin (50ml per 1000ml), stir well, and filter to obtain the product.

Embodiment 3

[0027] Example 3 Preparation of Periplaneta americana Ethanol Extract

[0028] Coarsely crush 1000kg of dried Periplaneta americana, add 500kg of water for every 100kg of coarse powder, soak for 2 hours, the temperature is about 80°C, extract three times, the first time is 8 hours; the second time add water 300kg, extract for 6 hours; the third time Add water 300kg at a time and extract for 4 hours. Combine the three extracts, filter, and concentrate the filtrate to a relative density of 1.10-1.20 (70°C), add 95% ethanol, keep stirring at 70°C for 30 minutes, let stand for 12 hours, discard the upper layer of grease, filter the lower layer of liquid medicine, Recover ethanol from the filtrate, concentrate under reduced pressure to a relative density of 1.20-1.25 (70°C), add purified water and glycerin (60ml per 1000ml), stir well, and filter to obtain the product.

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Abstract

An extract of American periplaneta and its medicinal composition with high content of general amino acids are disclosed. Its preparing process includes such steps as immersing American periplaneta in petroether for removing fat, extracting in water or alcohol, and mixing with pharmacologically acceptable additives.

Description

technical field [0001] The invention relates to a preparation method of an extract of Periplaneta americana, belonging to the field of medicine. Background technique [0002] Periplaneta americana (Latin name: Periplaneta americana), its distinguishing feature is that the adult is oval, the back and abdomen are flat, the body is yellowish brown, reddish brown or dark brown, and the body surface is shiny. It is large in size, with a body length of 25-45mm. There is a large dark brown butterfly-shaped spot on the pronotum. There is a "T"-shaped yellow stripe in front of the midline of the spot, which extends backward to the "small tail". Marginal spots are wider. Origin: Tropical or subtropical regions of Africa. Distribution status in my country: It is distributed all over the country, especially in southern China. [0003] At present, the preparation of Periplaneta americana extract is the national drug standard published by the State Drug Administration (Volume 19, the c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/64A61P1/00A61P9/00
Inventor 耿福能
Owner SICHUAN GOODDOCTOR PANXI PHARMA
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