Breast carcinoma transfer related gene chip establishment and its establishing method

A technology of gene chip and establishment method, applied in the field of gene chip preparation, to achieve good social and economic benefits
CN101008034AInactive Publication Date: 2007-08-01NANKAI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANKAI UNIV
Publication Date
2007-08-01
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses the establishment of gene chip relative to breast cancer transition and the establishment method. The gene chip comprises 218 genes, in which includes breast cancer transmission relative gene got by comparaing human breast cancer MCF-7 with human breast cancer system LM-MCF-7 (be awarded with patent for invention in China, ZL 03130264.5) with high transmission tendency, and breast cancer transmission relative gene reported by papers. Synthesizes oligonucleotide (oligo) with 218 genes, and spots molecular probe on plate modified by amino. Said prepared breast cancer transmission relative gene chip is mainly used for sifting anti- breast cancer transmission medicine, and states the molecular principle of medicine action, and can aslo be used for early- phase diagnosis for breast cancer transmission, assisting individual treatment program and prognosis judgement.
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Description

technical field

[0001] The invention relates to the design of gene chip probes for breast cancer metastasis-related genes, the preparation of gene chips, and the like. The gene chip is mainly used for the screening of anti-breast cancer metastasis drugs, early diagnosis of breast cancer metastasis, auxiliary individualized treatment plan and prognosis judgment, etc., belonging to the field of biotechnology. Background technique

[0002] The occurrence and development of breast cancer is a complex process involving multiple factors, multiple stages and multiple genes, and metastasis is the main cause of death of patients. If drugs against breast cancer metastasis can be obtained, it means that breast cancer metastasis can be treated more effectively. However, currently there is a lack of effective technical means for screening and identifying drugs that already have anti-breast cancer effects or whether newly developed drugs have the effect of inhibiting tumor metastasis. T...

Claims

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