Antimycotic externally used drug

An external medicine and antifungal technology, applied in antifungal agents, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of skin drug resistance, skin irritation, slow drug effect, etc., to promote tissue cell Effects of regeneration, less recurrence, and shortened course of treatment

Inactive Publication Date: 2008-02-27
程贵昌
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Dermatosis caused by fungal infection is a relatively stubborn disease that is difficult to cure completely. The common ones are tinea capitis, tinea manus, tinea pedis, jock itch, tinea corporis, etc. It is often unbearably itchy and contagious to a certain extent. The work brings a lot of inconvenience. Generally, external agents for treating antifungal skin diseases include miconazole, ketoconazole, clotrimazole, salicylic acid, acetic acid, etc...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0024] Take 10g of liquid paraffin, 5g of stearyl alcohol, and 2g of monoglyceride to make an appropriate amount of oil phase, add 1g of terbinafine hydrochloride or ketoconazole, and 0.02g of clobetasol propionate at 80°C; 2 g, 3 g of propylene glycol, and 0.03 g of methyl fat were used to prepare the water phase. Add the oil phase to the water phase at a temperature of 60-80°C and stir evenly; then cool down to 50-60°C and add 0.3 g of neomycin sulfate and stir evenly. When the temperature was cooled to 40 degrees, 20 g of water-soluble propolis was added, and 100 g of ointment was obtained through ultrasonic emulsification.

[0025] typical medical history

[0026] A man from Zhengzhou City, 45 years old, suffers from beriberi ulceration. He has been suffering from beriberi for many years. He has been using western medicine for many years. He often relapses and is very distressed. After using this preparation, the recurrent beriberi was cured after 14 days, and new skin gr...

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PUM

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Abstract

The invention discloses an externally-used medicament for treating skin mycosis diseases, which is prepared from the raw materials of (by weight percent) terbinafine hydrochloride or miconazole or ketoconazole 0. 5-2%, Clobetasol Propionate 0. 01-0. 2%, neomycin sulphate 0. 3-1%, bee glue 5-25%, and balancing distilled water.

Description

technical field [0001] The invention relates to an external medicine for skin, in particular to an external medicine for treating fungal skin diseases. Background technique [0002] Dermatosis caused by fungal infection is a relatively stubborn disease that is difficult to cure completely. The common ones are tinea capitis, tinea manus, tinea pedis, jock itch, tinea corporis, etc. It is often unbearably itchy and contagious to a certain extent. The work brings a lot of inconvenience. Generally, external agents for treating antifungal skin diseases include miconazole, ketoconazole, clotrimazole, salicylic acid, acetic acid, etc. Most of them are pure western medicines, and there are few external agents for traditional Chinese medicine. As far as the existing medicaments are concerned, most of the medicaments are slow to take effect, have certain irritation to the skin, and are likely to cause skin drug resistance and relapse easily. The combination of Chinese and Western medi...

Claims

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Application Information

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IPC IPC(8): A61K35/64A61K9/06A61K9/12A61P31/10A61K31/137A61K31/4164A61K31/496A61K31/573A61K31/7036A61K35/644
Inventor 程贵昌
Owner 程贵昌
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