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Use of iron(iii) complex compounds

A technology of complexes and compounds, applied in the application field of medicine, can solve the problems such as unfavorable parenteral application of iron dextran, and achieve the effect of improving immune defense and/or brain performance

Inactive Publication Date: 2008-04-02
VIFOR INT AG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Parenteral use of iron dextran is unfavorable because of the potential for glucose-induced anaphylactic shock

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0037] A treatment for patients with iron deficiency and patients with or Single center study of oral iron supplementation in adolescents without anemia comparing it with placebo.

[0038] The purpose of the comparative study was to study the effect of oral administration of iron(III)-polymaltose complex (100 mg iron per day and placebo, 6 days per week, for 8 months) on patients with iron deficiency anemia, Immune response, hematological status, cognitive function and behavioral function in four groups of adolescents with and without iron deficiency and anemia (iron supplementation) and another group without iron deficiency and anemia (placebo group) Impact.

[0039] For this purpose, 500 apparently healthy male and female adolescents between the ages of 15 and 18 were randomly selected and divided into the following groups using various hematological criteria.

[0040] Group

[0041] Each group included 30 test individuals and a total of 120 test individuals wer...

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Abstract

The present invention relates to novel therapeutic uses of iron(III) complex compounds with carbohydrates or derivatives thereof, in the preparation of a medicament for improving immune defense and / or brain performance.

Description

technical field [0001] The present invention relates to novel therapeutic applications of iron(III) complex compounds with carbohydrates or derivatives thereof, especially with dextrins or oxidation products of dextrins, especially in the preparation of compounds for improving immune defense and / or brain properties of pharmaceutical applications. Background technique [0002] Iron deficiency is the most common trace element deficiency worldwide. It affects children from infancy to adolescence not only in developing countries, but also affects many children in wealthy industrialized countries. In Canada, for example, 28% of adolescents showed signs of iron deficiency. [0003] The use of iron(III) oxide as an active ingredient for the treatment of immunodeficiency syndromes, especially AIDS, is known from WO 95 / 35113. [0004] A therapeutically applicable iron injection and a method for its preparation are known from DE 1467980 . [0005] From US 3076798 is known a proces...

Claims

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Application Information

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IPC IPC(8): A61K33/26A61K47/26A61P25/28A61P37/02
CPCA61K47/26A61K47/4823A61K31/716A61K31/295A61K33/26A61K9/0019A61K47/61A61P25/00A61P25/28A61P37/00A61P37/02A61P37/04A61P7/06
Inventor J·坦纳-鲍穆加特纳R·钱德拉P·盖瑟
Owner VIFOR INT AG
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