Tea polyphenol pellicle and method for making same
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A tea polyphenol film preparation and tea polyphenol technology are applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, which can solve the problems of unsatisfactory effect and high price, and achieve low cost. , good therapeutic effect
Inactive Publication Date: 2008-04-09
BEIJING UNION GENIUS PHARMA TECH +1
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Problems solved by technology
The price of these drugs is high, and the effect of clinical application is not ideal. The reason is that there are a large number of proteases in the chronic ulcer wound, which decomposes the endogenous growth factors secrete...
Method used
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Embodiment 1
[0014] Tea polyphenols 20g, vitamin B 12 3g, polyvinylpyrrolidone 75g, glycerol 2g, distilled water 1000ml, soak polyvinylpyrrolidone in water, and heat it to dissolve in a water bath at 30℃, filter, and add tea polyphenols and vitamin B into the filtrate in proportion 12 , Glycerin, mix well, remove bubbles, apply film, dry, and cut to obtain tea polyphenol film product.
Embodiment 2
[0016] Tea polyphenols 60g, vitamin B 12 3g, 45g sodium carboxymethylcellulose, 9g sorbitol, 1000ml distilled water, soak the sodium carboxymethylcellulose in water, and heat it to dissolve in a water bath at 80℃, filter, and add tea polyphenols and vitamin B to the filtrate in proportion 12 , Sorbitol, mix well, remove bubbles, coat, dry, and cut to obtain tea polyphenol film product.
Embodiment 3
[0018] Tea polyphenols 50g, vitamin B 12 1.5g, gum arabic 40g, glycerol triacetate 16g, distilled water 1000ml, soak gum arabic in water, and heat to dissolve in a water bath at 50℃, filter, and add tea polyphenols and vitamin B to the filtrate in proportion 12 , Triacetin, mix well, remove bubbles, apply film, dry, and cut to obtain tea polyphenol film product.
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Abstract
The invention discloses tea polyphenol film agent and the preparation method thereof which are used for the treatment of chronic ulcer of skin. Tea polyphenol and vitamin B12are taken as the main component, and the film agent is produced by adding auxiliary materials of film forming material and plasticizer, etc. The preparation method comprises the following steps: the film forming material is soaked in water, heated and dissolved in a water bath at 30 to 80 DEG C, and filtered, the tea polyphenol, the vitamin B12, and the plasticizer are added into the filtrate in proportion, uniform mixing, air bubble removing, film coating, drying and parting cut are performed, and then the tea polyphenol film agent product is obtained. The film agent of the invention can be effectively used to treat diabetes foot ulcer, hansens disease ulcer and other chronic ulcers of skin, and also used to treat skin ulcer caused by burn and scald, can quicken the healing of ulcers, increase the scarfskin complete coverage percentage, the ulcers are uneasy to recur, the film agent is safe and non-toxic, and the cost is low.
Description
Technical field [0001] The invention discloses a film agent and a preparation method thereof, in particular to a film agent for treating chronic skin ulcers and a preparation method thereof, and belongs to the field of biomedicine. Background technique [0002] Chronic skin ulcers, also known as refractory ulcers, are common clinical diseases, such as diabetic foot ulcers, leprosy ulcers, etc., which often do not heal for a long time and are prone to recurrence. Due to high blood sugar and low resistance, diabetic patients have low ability to repair wounds on their own, which makes it difficult for wounds to heal and increases the chance of infection. Leprosy, tuberculosis and syphilis are known as the three major chronic infectious diseases. It is a disease in which a kind of mycobacterium in nature invades human skin and peripheral nervous system, causing skin damage and limb deformity. Nerve and vascular dysfunction ulcers caused by leprosy are secondary local tissue ulcers, m...
Claims
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Application Information
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