A technique for preparing absorbable gelatin sponge particle suppository with glutin as raw material
A technology of gelatin sponge and embolic agent, which is applied in the field of interventional medicine, can solve the problems that the residual amount of formaldehyde is difficult to reach the clinical standard, and the raw materials are expensive, and achieve the effect of low cost and broad application prospects
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Embodiment 1
[0027] (1) Take 28g of 250ps gelatin raw material, put it in a 500ml beaker, add 350ml of water for injection, stir for 1min, then let it stand for swelling for 1h, until the gelatin particles are transparent;
[0028] (2) Under the condition of a water bath at 20°C, the above-mentioned gelatin solution was stirred and dissolved until the solution was transparent;
[0029] (3) Transfer the dissolved transparent gelatin solution to a 2000ml beaker, heat it in a water bath at 20°C, stir with an electric mixer, and add a concentration of 1% formaldehyde solution while stirring under the condition of low-speed stirring 60ml, cover with plastic paper, when foam appears, increase the speed of the mixer to a high speed (2000 rpm), stir for 15min, and stop stirring when the gelatin solution is uniform and delicate foam (volume is about 1600ml), and The solution was quickly transferred to the freezer, the freezing time was 5 hours, and the freezing temperature was -50°C until it became...
Embodiment 2
[0041] (1) Take 28g of 250ps gelatin raw material, put it in a 500ml beaker, add 350ml of water for injection, stir for 1min, then let it stand for swelling for 1h, until the gelatin particles are transparent;
[0042] (2) Under the condition of a water bath at 50°C, the above-mentioned gelatin solution was stirred and dissolved until the solution was transparent;
[0043] (3) Transfer the dissolved transparent gelatin solution to a 2000ml beaker, heat it in a water bath at 50°C, stir with an electric mixer, and add a concentration of 15% formaldehyde solution while stirring under the condition of low-speed stirring 30ml, cover with plastic paper, when foam appears, increase the speed of the mixer to a high speed (2000 rpm), stir for 15min, and stop stirring when the gelatin solution is uniform and delicate foam (volume is about 1600ml), and The solution was quickly transferred to the freezer, the freezing time was 50 h, and the freezing temperature was -5°C until it became wh...
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