Intermediate compound of a traditional Chinese medicinal preparation and preparation method and application thereof

Abstract

The invention discloses an intermediate of a liquid Chinese medicine preparation, the preparation and the application thereof, the invention includes pulverization method of single leech ultrafine powder, in particular to a pulverization method of preparing leech ultrafine powder by wet-method ultrafine pulverization method. The method is that leech medical material is pulverized through a traditional method, then added with any one or the compositions of a plurality of gum acacia, betadex, starch and solid carbowax with proper quantity, and then undergone ultrafine pulverization to obtain the preparation intermediate; the intermediate products can be prepared into required dosage forms. This method can improve pulverization efficiency and decrease raw material usage amount in the products.

Description

technical field [0001] The invention relates to an intermediate of a leech-containing single medicinal material preparation and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] 1. Research progress of leeches [0003] The effect of leech is to break blood, expel blood stasis, and eliminate symptoms. It can be used for lumps in the abdomen, blood stasis, amenorrhea, bruises, thrombocytosis, and cerebral hemorrhage. Leeches were first recorded in "Shen Nong's Materia Medica": "The main purpose is to drive away bad blood, blood stasis, moon closure, accumulation of broken blood, no children, and water passages." Salty and bitter, in order to remove blood accumulation, it is the medicine of the liver meridian blood, so it can dredge the liver meridian and gather blood." [0004] The curative effect of leeches is definite, and it has extremely high medicinal value and economic value. Its pharmacological effect...

AI Technical Summary

Problems solved by technology

[0005] The active ingredients of leeches are not clear, and the literature reports that proteins, polypeptides, trace elements, etc. are the active ingredients. The ambiguity of the active ingredients is an inherent problem of animal medicinal materials. Traditional extraction and concentration methods are used to decompose some ingredients. , damage, or cannot be extracted, it is easy to lose the active ingredients, and it is not suitable for animal medicinal materials. Combining animal drug research with modern technology will break through the bottleneck in animal drug research and be widely used in deep-seated fields.