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Surgical stent having micro-geometric patterned surface

A surgical, microscopic technique used in the field of surgical stents

Inactive Publication Date: 2008-06-04
BIOLOK INT
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0018] However, the aforementioned references do not teach the use of microscopically patterned surfaces on surgical stents to control or inhibit the proliferation of smooth muscle cells in the lumen of the stent

Method used

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  • Surgical stent having micro-geometric patterned surface
  • Surgical stent having micro-geometric patterned surface
  • Surgical stent having micro-geometric patterned surface

Examples

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Embodiment Construction

[0031] In one embodiment, the present invention provides a surgical scaffold having a surface that is microscopically geometrically patterned to inhibit the proliferation of smooth muscle cells within the lumen of the scaffold.

[0032] like figure 1 As shown, surgical stent 100 has a generally cylindrical stent frame 110 configured for implantation in a body lumen, such as an artery, an esophageal stent, or a ureter. like figure 2 As shown in the partially enlarged view of the outer surface 120 of the stent frame 110 shown in FIG. 6. exist figure 2 In , black lines represent microgrooves 4 , and white areas between adjacent microgrooves represent ridges 6 . The structures of the fine grooves 4 and the ridges 6 will be described in detail below.

[0033] It should be understood that the stent frame may comprise various structural components and structures which may include, but are not limited to, helically articulated slotted tubes, sinusoidal patterns, curved sections...

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Abstract

A surgical stent having thereon micro-geometric patterned surface and the method of use for inhibiting smooth muscle cell growth into stent lumen are disclosed. The surgical stent has a generally cylindrical stent frame configured to be implanted into a body lumen, and the stent frame has thereon a micro-geometric patterned surface with includes a multiplicity of microgrooves distributed in a pre-determined pattern. Each of the microgrooves has a width in a range of from about 4 to about 40 microns and a depth in a range of from about 4 to 40 microns. The surgical stent can further include drug wells, and the surgical stent can have a biocompatible chemical compound, such as thrombosis inhibitor or cell growth inhibitor, embedded in the microgrooves or drug wells.

Description

[0001] Cross References to Related Applications [0002] This application claims priority under 35 USC 119(e) to Provisional Patent Application 60 / 550,130, filed March 4, 2004, which is hereby incorporated by reference. technical field [0003] The present invention relates to a surgical stent for implantation in a body cavity such as an artery. More specifically, the present invention relates to a surgical stent having a microscopic geometrically patterned surface on the stent frame to inhibit the growth of smooth muscle cells in the lumen of the stent and reduce in-stent restenosis. Background technique [0004] It has long been known that surgical stents can be surgically implanted into body cavities, such as arteries, to reinforce, support, repair or improve the performance of the body cavity. For example, in cardiovascular surgery, it is often necessary to place a stent in a coronary artery at a location where the artery is damaged or prone to collapse. Once the stent...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/06A61F2/00A61F2/90
CPCA61F2/91A61F2002/9155A61F2/0077A61F2002/0081A61F2250/0068A61F2002/91533A61F2/915
Inventor 哈罗德·亚历山大约翰·L·里奇
Owner BIOLOK INT
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