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Chinese medicinal composition for curing critter bow-shaped vermination and preparation method and application thereof

A technology for toxoplasmosis and a composition is applied in the field of traditional Chinese medicine compositions for livestock, which can solve the problems of bacteria producing drug-resistant strains, large liver and kidney side effects, human harm, etc., and achieves avoiding veterinary drug residues and social pollution, long course of treatment, and difficulty in avoiding veterinary drugs. effect of recurrence

Inactive Publication Date: 2010-12-15
周广生 +2
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Sulfonamides have great side effects on liver and kidney. If the liver and kidney function of sick animals are not good, sulfonamides cannot be used in general, which brings difficulties to the treatment of this disease. At the same time, long-term use of sulfonamides can make some bacteria resistant strains
After the use of yellow amine drugs, there are still drug residues in animal products, which also caused direct harm to humans

Method used

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  • Chinese medicinal composition for curing critter bow-shaped vermination and preparation method and application thereof
  • Chinese medicinal composition for curing critter bow-shaped vermination and preparation method and application thereof
  • Chinese medicinal composition for curing critter bow-shaped vermination and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Prescription: 4 grams of cinchona; 8 grams of betel nut; 7 grams of lampstand tree; 6 grams of licorice.

[0052] Concrete preparation process is as follows:

[0053] a. Soak cinchona, betel nut, lampstand tree, licorice and 3-4 times the total weight of 4 traditional Chinese medicines in distilled water for 24 hours, decoct 3 times, keep for 0.5 hours after each boil, combine the decoction and concentrate until thick shape.

[0054] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 60%, fully stir and mix, precipitate, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 70%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until there is no alcohol smell, add 4 times the amount of distilled water to the medicinal solution, refrigerate and precipitate for 48 hours, filter, and the filtrate ...

Embodiment 2

[0057] Prescription: 8 grams of cinchona; 16 grams of betel nut; 14 grams of lampstand tree; 12 grams of licorice.

[0058] a. Soak cinchona, betel nut, lampstand tree, licorice and 3-4 times the total weight of 4 traditional Chinese medicines in distilled water for 30 hours, decoct 3 times, keep for 1 hour after each boil, combine the decoction and concentrate until thick shape.

[0059] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 65%, stir and mix thoroughly, precipitate for 60 hours, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 75%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until it has no alcohol smell, add 2 times the amount of distilled water to the medicinal solution, refrigerate and precipitate for 24 hours, filter, and the filtrate concentrate.

[0060] c. the medicin...

Embodiment 3

[0062] Prescription: 16 grams of cinchona; 32 grams of betel nut; 28 grams of lampstand tree; 24 grams of licorice.

[0063] a. Soak cinchona, betel nut, lampstand tree, licorice and 5 times the total weight of 4 traditional Chinese medicines in distilled water, soak for 27 hours, decoct 3 times, keep for 1 hour after each boil, combine the decoction and concentrate until thick.

[0064] b. Add 95% ethanol to the concentrated solution to adjust the alcohol concentration to 70%, stir and mix thoroughly, precipitate for 48 hours, filter, and recover ethanol from the filtrate. Add ethanol to the medicinal solution after recovering ethanol to adjust the alcohol concentration to 80%, stir and precipitate for 48 hours, filter, recover the ethanol from the filtrate and concentrate until it has no alcohol smell, add 2 times the amount of distilled water to the medicinal solution, refrigerate and precipitate for 48 hours, filter, and the filtrate concentrate.

[0065] c. the medicinal...

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Abstract

The invention discloses a traditional Chinese medicine combination for treating livestock toxoplasmosis and a preparation method and the application thereof. The traditional Chinese medicine combination adopts ledger cinchona, areca catechu, giant dogwood and glycyrrhiza to be added with distilled water, the solution is decocted for three times, the decocting solution obtained from the three times is merged and concentrated to condensed state, ethanol of 95 percent is added until the ethanol concentration of the solution reach 60 percent to 70 percent, then the solution is precipitated and filtered, and filter liquor is concentrated. The medical solution after being concentrated is added with the ethanol of 95 percent until the ethanol concentration of the solution reach 75 percent to 80 percent, the solution is precipitated and filtered, and the filter liquor is concentrated. The medical solution after being concentrated is added with the distilled water, then the solution is chilled, precipitated, filtered and concentrated, so as to form the concentration that 2g crude drugs are contained in one milliliter; the solution is separately packed and sterilized, so that the traditional Chinese medicine combination is obtained. The cure rate on the livestock toxoplasmosis by adopting the traditional Chinese medicine combination can reach about 98 percent, the side-effect is small, the use is safe and convenient, the dose is small, and the absorption is quick.

Description

Technical field: [0001] The invention belongs to the field of traditional Chinese medicine pharmacy, and relates to a traditional Chinese medicine composition for livestock. The invention also relates to a preparation method of the traditional Chinese medicine composition and the use of the traditional Chinese medicine composition in treating swine toxoplasmosis and other livestock toxoplasmosis, tapeworm and roundworm Application in veterinary medicine for diseases. Background technique: [0002] Toxoplasma gondii is a zoonotic parasitic disease, all kinds of livestock can be infected, but the incidence of pigs is relatively high, the pathogen of this disease was only known in the 1970s, and the treatment method was studied. For the treatment of this disease, sulfa drugs have been used. Although there are certain effects, intramuscular injection of sulfa drugs is more irritating to the tissue, intravenous injection is troublesome, and the course of treatment is longer. Sul...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/889A61P33/02A61P33/14A61K31/045
Inventor 周广生刘俊栋朱善元刘海霞贺生中吴桂银吴军民
Owner 周广生