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Compound mequindox soluble powder for animals and preparation thereof

A technology of compound methaquine and methaquine, which is applied in the direction of medical preparations containing active ingredients, powder delivery, and pharmaceutical formulations, can solve the problems of delaying the best treatment time, widespread drug resistance, and difficult disease treatment, etc. Achieve the effects of avoiding drug residue exceeding the standard, simple preparation method and process, and reducing use cost

Inactive Publication Date: 2008-11-12
TIANJIN SHENGJI GRP CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Colistin sulfate is an effective drug against Escherichia coli, and due to the same large-scale use as acemethaquine, drug resistance is common and the therapeutic effect is reduced. increase, so that the two drugs alone can not achieve satisfactory therapeutic effect
When the two are used in combination, because the acetylmethaquine powder cannot be dissolved in water, and the colistin sulfate soluble powder is dissolved in water, because these two medicines cannot all be dissolved in water, and pigs suffer from dysentery and colibacillosis and cause diarrhea, generally They don't like food but like drinking water, which causes the feed intake problem caused by the disease to fail to achieve the therapeutic effect during treatment.
Moreover, it is inconvenient for farmers to use, and it is prone to the phenomenon of drug waste due to insufficient or overdose of a certain drug, and it is uneconomical for users to use
At the same time, for farmers, it is not easy to determine the disease, and it is impossible to prescribe the right medicine, which brings difficulties to the treatment of the disease, and sometimes even delays the best treatment time

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] (1) Sieve acetylmequine, colistin sulfate, sodium salicylate, and oral glucose through a 24# sieve for later use.

[0021] (2) Take 2 kg of sieved methaquine, 5 kg of colistin sulfate, and 6 kg of sodium salicylate and mix them fully in a V-shaped mixer for 30 minutes.

[0022] (3) Add 87kg of sieved oral glucose into the mixture of above-mentioned acemetquine, colistin sulfate, and sodium salicylate, fully mix in a common mixer for 30 minutes, discharge, and pass through a 24# sieve to obtain The compound acemetquine soluble powder of the present invention.

Embodiment 2

[0024] (1) Sieve acetylmequine, colistin sulfate, sodium salicylate and oral glucose through a 24# sieve, and set aside.

[0025] (2) Weigh 10 kg of sieved acemetquine, 0.5 kg of colistin sulfate, and 30 kg of sodium salicylate, and fully mix them in a V-shaped mixer for 30 minutes.

[0026] (3) Add 59.5 kg of sieved oral glucose powder into the mixture of the above-mentioned acetylmequine, colistin sulfate, and sodium salicylate, fully mix in a common mixer for 30 minutes, discharge, and pass 24# Sieve to obtain the compound recipe acemetquine soluble powder of the present invention.

Embodiment 3

[0028] (1) Sieve acetylmequine, colistin sulfate, sodium salicylate and oral glucose through a 24# sieve, and set aside.

[0029] (2) Take 3 kg of sieved acemetquine, 4 kg of colistin sulfate, and 9 kg of sodium salicylate and fully mix them in a V-shaped mixer for 30 minutes.

[0030] (3) Add 84 kg of sieved oral glucose powder into the mixture of above-mentioned acetylmequine, colistin sulfate, and sodium salicylate, fully mix in a common mixer for 30 minutes, discharge, and pass through a 24# sieve Obtain the compound recipe acemetquine soluble powder of the present invention.

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PUM

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Abstract

The invention discloses a compound mequindox soluble powder for animals and a preparation method thereof, which aims to provide the compound mequindox soluble powder for the animals and the preparation method, wherein, the compound mequindox soluble powder for the animals can treat the complex infection of shigella shigae and colon bacillus of pigs, is quick to take effect, can solve the treatment failure phenomenon caused by feeding and drinking conditions of the pigs during the illness, and improve the rate of liveweight growth; and the preparation method has a simple process and is easy to realize. The powder comprises the compositions in percentage by weight: 2 to 10 percent of mequindox, 0.5 to 5 percent of colistin sulfate, 6 to 30 percent of sodium salicylate, and the balance being oral glucose. The soluble powder is a compound preparation formed by a double antimicrobial drug combined with a suspending agent, has quick effect on the complex infection of the shigella shigae and the colon bacillus of the pigs due to the fact that the mequindox and the colistin sulfate are jointly used, is effective and highly efficient, can solve the treatment failure phenomenon caused by feeding and drinking problems during the illness, accelerate the recovery of the pigs, and increase the weight of the pigs.

Description

technical field [0001] The invention relates to a veterinary compound acetylmethaquine soluble powder and a preparation method thereof. Background technique [0002] The mixed infection of swine dysentery and Escherichia coli is a disease that often occurs in pigs in recent years. The mixed infection of swine dysentery and Escherichia coli mainly affects the digestive system of pigs, causing severe diarrhea, and because of the mixed infection, the mortality rate of pigs is greatly increased, and the Cause very big trouble to the diagnosis of disease, bring very big trouble to veterinarian and breeder, give great loss to some breeder. [0003] At present, because acemethaquine can specifically kill dysentery caused by dysentery bacillus, it also has a certain effect on Escherichia coli. Due to extensive use and long-term use, the bacteria have high drug resistance, and treatment failure often occurs. Colistin sulfate is an effective drug against Escherichia coli, and due to ...

Claims

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Application Information

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IPC IPC(8): A61K9/14A61K31/498A61K38/12A61K31/60A61P31/00A61P1/12
Inventor 徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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