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Traditional Chinese medicine for preventing and treating metabolism syndrome

A technology for metabolic syndrome and compound preparations, applied in the field of traditional Chinese medicine preparations, can solve problems such as accelerated insulin resistance, lipid metabolism disorders, etc.

Inactive Publication Date: 2008-11-26
TIANJIN DANXI TCM INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, there are no Chinese and Western medicines that can lower blood sugar and lower lipids in the market. Blind pursuit of lowering blood sugar will undoubtedly make the pancreatic islets that are gradually desensitized worse, accelerate insulin resistance, and induce lipid metabolism disorders instead.

Method used

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  • Traditional Chinese medicine for preventing and treating metabolism syndrome
  • Traditional Chinese medicine for preventing and treating metabolism syndrome

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] Embodiment 1: the preparation of extract

[0032] Prescription: Digupi 9 servings

[0033] Coptis 0.6 part

[0034] Epimedium 3 parts

[0035] 3 parts cinnamon

[0036] Pueraria 6 servings

[0037] Turmeric 3 parts

[0038] Operation: Take the above five flavors, take Digupi, turmeric, cinnamon and add 6 times the amount of ethanol to reflux and extract twice, each time for 2 hours, combine the extracts, filter, and recover the ethanol under reduced pressure until there is no alcohol smell, and set aside; The coarse powder of the mesh sieve was soaked overnight with 1% sulfuric acid, and percolated with 1% sulfuric acid at a percolation rate of 25ml / min until there was no alkaloid reaction. Batch percolation for later use, adjust pH to 6-7 with lime milk, set aside for filtration at around 0°C, filter with suction, discard the precipitate, adjust the filtrate to pH 1-2 with hydrochloric acid, set aside overnight at around 0°C, filter w...

experiment example 2

[0039] Experimental Example 2: Tablet Preparation

[0040] Prescription: Example 1 extract 100 parts

[0041] 1 part pregelatinized starch

[0042]1 part stearic acid

[0043] Talc powder 0.5 parts

[0044] Carboxymethyl starch sodium 0.5 parts

[0045] 1 part dextrin

[0046] Preparation method: Mix evenly, granulate, pass through 20 sieves, and press into tablets. 0.3g / piece

[0047] Take 2 tablets each time, 3 times a day

experiment example 3

[0048] Experimental Example 3: Preparation of Soft Capsules

[0049] Prescription: 100 parts of the extract of Example 1

[0050] Accessory salad oil 98 parts

[0051] 1 part palm oil

[0052] 1 part beeswax

[0053] Preparation method: Colloidal mill mixing, pressing soft capsules. 0.56g / capsule, oral administration: 1 capsule / time, 3 times / day.

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Abstract

The invention relates to a traditional Chinese medicine prescription preparation for preventing and treating metabolic syndrome. The traditional Chinese medicine prescription preparation is the traditional Chinese medicine compound preparation which is composed of cortex lycii, golden thread, epimedium herb, cassia bark, kudzuvine root and turmeric. The preparation has the advantages that: 1. the preparation has the effects of clearing heat, moistening dryness, nourishing yin, promoting fluid production, invigorating spleen and kidney yang deficiency, activating blood circulation, removing blood stasis and treating both manifestation and root cause of the disease, thus being used for the metabolic syndrome and significantly improving the symptoms of the metabolic syndrome; 2. the animal experiments show that the preparation can not only have the significant and durable effect on lowering blood sugar, but can also have the significant effect on lowering lipid and regulating liquid, preventing the damages of large blood vessels of diabetic patients and causing the diabetic patients with the early-stage damaged large blood vessels to be reversed; 3. and the animal experiments show that the toxicity is very low and the administration is safe. 4. The extraction process is advanced, the administration amount is small, and the preparation can be made into various formulations, thus facilitating the production, the storage, the transportation, the carrying and the usage.

Description

Technical field: [0001] The invention belongs to a traditional Chinese medicine prescription, in particular to a traditional Chinese medicine prescription for preventing and treating metabolic syndrome. Background technique: [0002] According to a document published by the International Diabetes Federation, in the past 20 years, the number of diabetic patients in the world has increased dramatically from 30 million to 230 million. Among the ten countries with the largest number of diabetic patients in the world, seven are developing countries, and China is at the top of the list. There are currently 50 million diabetics in China, and the number will double in the next two to three years. The World Health Organization predicts that by 2015, Chinese diabetics will exceed 100 million. [0003] The greatest danger of diabetes is mainly manifested in its chronic complications. 96% of diabetic patients suffer from various degrees of chronic complications. Metabolic syndrome is ...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61K9/16A61K9/20A61K9/48A61P3/06A61P3/10A61P9/12
Inventor 孔伶俐魏吉城
Owner TIANJIN DANXI TCM INST
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