Microelectro field net guided transfer apparatus for medicament in hepar target cell

Abstract

The invention provides a drug transfer device in the liver targeting cells led by a micro electric field net and pertains to the medical field. The drug transfer device comprises a drug transfer pipe, which is characterized in that at least two drug input holes and a first electrode group are arranged at the front end of the drug transfer pipe; a second electrode group is arranged out of the liver; the first and the second electrode groups are electrically connected with the impulse output end of a generator with low pressure and micro electric field; and the drug transfer pipe is communicated with the drug transfer device. By providing a multidimensional / three-dimensional low / micro pressure electric field, 'permeability' of cell membrane can be improved obviously, and the acceptance dosage of targeting cells or organs is increased greatly. Not only the targeting cells or organs can not be injured, but also the targeting performance aiming at liver cancer cells is improved to an extreme extent and the side effects to the whole body of a sufferer is lowered. The drug transfer device can be extensively used in the clinic application field of drug / gene treatment.

Description

technical field [0001] The invention belongs to the medical field, and in particular relates to a medical device for delivering medicine to a designated target and helping to increase its permeability. Background technique [0002] Primary hepatocellular carcinoma (hereafter referred to as liver cancer), also known as liver tumor, is the most common malignant primary liver tumor. Liver cancer is one of the top three deadly cancers in many Asian and African countries. [0003] According to statistics from the Ministry of Health, about 130,000 people die from liver cancer every year in my country, accounting for 40% of the total number of deaths from liver cancer in the world. [0004] The onset of liver cancer is relatively insidious, and when there are obvious clinical symptoms, it is already in the middle and late stage. Surgical resection only accounts for 10-15% of liver cancer patients, and even if resection is performed, the recurrence rate is as high as about 60%. B...

AI Technical Summary

Problems solved by technology

This method can only work on the tissue around the injection needle and within the diameter of <0.8 cm, and the acupuncture damage is also large. It can only be used on the body surface at most, and cannot be used on large organs in the human body, such as the heart, liver, and lungs. , kidney etc.

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