Compound gentamicin-micronomicin injection and preparation method

A technology of gentamicin sulfate and micronomycin, which is applied in medical formulas, medical preparations containing active ingredients, drug delivery, etc., can solve the problems of excessive drug residues and reduced curative effect, so as to relieve the body's stress response and improve the curative effect. The effect of enhancing and strengthening the body's resistance

Inactive Publication Date: 2009-03-04
TIANJIN SHENGJI GRP CO LTD
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  • Abstract
  • Description
  • Claims
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Problems solved by technology

Over the years, streptomycin and quinolones have been listed as the first-selected drugs for the treatment of bacterial gastrointestinal infections in pigs, cattle, sheep, and horses. Due to the

Method used

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Examples

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Example Embodiment

[0018] The present invention will be further described below in conjunction with the specific examples in the table below, wherein the unit is the number of parts, and each part is 500g.

[0019] Example 1 Example 2 Example 3 Example 4 Example 5 Gentamic Sulfate-Micronomycin 80 100 110 90 95 Aminopyrine 60 80 100 150 130 bethanechol chloride 7 5 20 10 15 Dexamethasone Sodium Phosphate 5 10 15 20 2 95% ethanol 200 250 100 400 300

[0020] Describe the preparation method of Compound Boluohui Injection in detail with Example 1

[0021] (1) Take by weight 80 parts of gentamicin sulfate-micronomycin, 60 parts of aminopyrine, 7 parts of bethanechol chloride, 5 parts of dexamethasone sodium phosphate, 200 parts of 95% ethanol;

[0022] (2) Put the aminopyrine into the 95% ethanol, stir for 10-25min until clear;

[0023] (3) Get 300 parts of water for injection, add genta sulfate-micronomycin, bethanechol chlori...

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Abstract

The invention provides a compound gentamycin-micronomicin injection which causes the causative organisms to be not easy to generate drug resistance and a preparation method thereof. The injection comprises 80 to 110 parts of compound gentamycin-micronomicin, 60 to 150 parts of aminopyrine, 5 to 20 parts of bethanechol chloride, 2 to 20 parts of dexamethasone sodium phosphate, and 100 to 400 parts of 95-percent ethanol. The preparation method comprises the following steps: aminopyrine is put into 95-percent ethanol, and is stirred for 10 to 25 minutes to become transparent; 300 parts of water for injecting is taken, gentamycin-micronomicin, bethanechol chloride, dexamethasone sodium phosphate are added in sequence to water, and stirred until being dissolved, and the liquid is mixed; the injection is stirred evenly, and kept for 15 to 20 minutes; when the liquid medicine becomes transparent, 1000 parts of water for injection is added, so that the injection is obtained. By adopting a polypharmacy pharmaceutical, the injection is effective for bacterial stomach intestine of a pig, a cow, a sheep and a horse, the resistance of an organism is enhanced, both the symptoms and the root causes are addressed, and the stress reaction of an animal body is eased.

Description

technical field [0001] The invention relates to the field of drug injections, in particular to a compound genta sulfate-minornomycin injection and a preparation method thereof. Background technique [0002] Bacterial gastrointestinal tract infection is a highly susceptible disease for pigs, cattle, sheep, and horses, and can cause diarrhea and diarrhea in pigs, cattle, sheep, and horses. [0003] The main pathogenic bacteria of this disease are pathogenic Escherichia coli, Salmonella, etc., among which these bacteria have permanent residence in livestock, under normal conditions, Escherichia coli, Salmonella, etc. are beneficial bacteria that help livestock digest However, when the environment changes or the resistance of livestock decreases, these bacteria may become pathogenic bacteria and cause livestock infection. Over the years, streptomycin and quinolones have been listed as the first-selected drugs for the treatment of bacterial gastrointestinal infections in pigs, c...

Claims

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Application Information

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IPC IPC(8): A61K9/08A61K31/7036A61P31/04A61P1/04
Inventor 魏宗生徐克福
Owner TIANJIN SHENGJI GRP CO LTD
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