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Ribavirin soluble powder

A soluble powder, ribavirin technology, applied in the directions of antiviral agents, powder delivery, organic active ingredients, etc., can solve the problems of uneven administration, high cost, troublesome operation, etc., and achieves simple use, convenient transportation, and low cost. low cost effect

Inactive Publication Date: 2009-03-25
上海恒丰强生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] From the above-mentioned reported ribavirin dosage forms, it can be seen that when large-scale breeding animals, especially non-food animals, are administered, there are defects such as high cost, uneven administration, troublesome operation, and huge emergency response of animals using the drug.

Method used

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  • Ribavirin soluble powder
  • Ribavirin soluble powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] 1. Commercial raw materials: ribavirin, fosfomycin sodium, flavoring (musk flavoring or cinnamon flavoring), soluble flavoring agent (sucrose, lactose or sodium saccharin) and soluble filler (soluble starch or glucose);

[0027] 2. Dry the above-mentioned raw materials so that their water content is less than 5%;

[0028] 3. Weigh the raw materials of the following components

[0029] Ribavirin 5g

[0030] Fosfomycin Sodium 2g

[0031] Musk fragrance 0.1g

[0032] Glucose balance;

[0033] 4. The raw materials of the above components are fully pulverized, and sieved with a 300 mesh sieve;

[0034] 5. Fully stir the above-mentioned raw materials after sieving, and mix evenly;

[0035] 6. Sampling and testing to check the percentage of raw material content, whether the fineness of the powder meets the standard, whether the water content is qualified, etc.;

[0036] 7. Measure and weigh, pack into bags, and fill each bag with 5 grams, 10 grams or 100 grams of the abo...

Embodiment 2

[0038] One, the first two steps are operated with embodiment 1;

[0039] 2. Weigh the raw materials of the following components

[0040] Ribavirin 10g

[0041] Fosfomycin Sodium 5g

[0042] Cinnamon Spice 0.3g

[0043] Sodium saccharin 10g

[0044] Soluble starch balance;

[0045] Three, next operation is the same as embodiment 1.

Embodiment 3

[0047] One, two-step operation is with embodiment 1;

[0048] 2. Weigh the raw materials of the following components

[0049] Ribavirin 15g

[0050] Fosfomycin Sodium 8g

[0051] Musk fragrance 0.5g

[0052] 20 grams of sucrose

[0053] Soluble starch balance;

[0054] Three, next operation is the same as embodiment 1.

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Abstract

The invention relates ribavirin soluble powder and the preparation method thereof. Ribavirin, and fosfomycin sodium are used as main ingredients, together with proper amount of perfume, soluble flavoring agent and soluble filler; the ribavirin soluble powder is prepared through the following conventional methods, drying, weighing, crushing, stirring, homogenized mixing, inspection, measuring and packing. The ribavirin soluble powder has the advantages of simple application, low cost, complete aroma, stable storage, convenient transportation and good water solubility; the ribavirin soluble powder can be prepared into drinking agent to improve the treatment effect of ribavirin for the non-food animals so that the ribavirin soluble powder is special non-food animal powder which is novel, broad-spectrum and efficient.

Description

technical field [0001] The invention relates to a ribavirin soluble powder and a preparation method thereof. The ribavirin soluble powder is non-food and specially used for animals. Background technique [0002] Ribavirin (Ribavirin, ribavirin, ribavirin, ribavirin ICN, RTC), chemical name: 1-β-D-ribofuranosyl-1H-1,2,4-triazole- 3-carboxamide, its structure is as follows: [0003] [0004] The drug is a broad-spectrum potent antiviral nucleoside drug, which has been included in the national basic medicinal products, and is effective against at least 12 kinds of RNA viruses (type A, B influenza virus, type 1, type 3 parainfluenza virus, Korean hemorrhagic fever virus, Argentine hemorrhagic fever virus, rhinovirus respiratory syncytial virus, Bolivia hemorrhagic fever virus, Rift Valley fever virus, Lassa virus, murine encephalitis myocarditis virus) and 10 DNA viruses (herpes simplex virus type 1, 2 , adenovirus, myxovirus, vaccinia virus, herpes zoster virus, human cyto...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/14A61K31/7056A61K31/662A61P31/12
Inventor 龙谭汤芝平蔡友界廖洪程明镜
Owner 上海恒丰强生物技术有限公司
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