Two-dimensional digital microfluid analysis test platform based on acoustic surface wave

A surface acoustic wave and detection platform technology, applied in biological testing, material inspection products, etc., can solve problems such as the inability to realize digital microfluidic drive, achieve the effect of less liquid volume, overcome the complexity of manufacturing process, and fast analysis speed

Inactive Publication Date: 2009-10-14
SHANGHAI JIAO TONG UNIV
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  • Abstract
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  • Claims
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Problems solved by technology

The disadvantage of this device is that it can only realize one-dimensional digital microfluidic drive, but not two-dimensional digital microfluidic drive.

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  • Two-dimensional digital microfluid analysis test platform based on acoustic surface wave
  • Two-dimensional digital microfluid analysis test platform based on acoustic surface wave

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Embodiment Construction

[0015] The embodiments of the present invention will be described in detail below with reference to the accompanying drawings: this embodiment is implemented on the premise of the technical solution of the present invention, and detailed implementation modes and specific operating procedures are given, but the scope of protection of the present invention is not limited to the following Mentioned examples.

[0016] Such as figure 1 As shown, this embodiment includes four sets of metal comb-shaped interdigital electrode pairs 1, 2, 3, 4 with the same size and symmetrically distributed, a lithium niobate substrate 5, a patterned hydrophobic coating 6, and a two-dimensional affinity Water rail 7, in which the bottom layer is a lithium niobate substrate 5, the center of the upper layer is a patterned hydrophobic coating 6, and the two-dimensional hydrophilic guide 7 is evenly distributed on the patterned hydrophobic coating 6. The intersection is a node, and four sets of metal comb-sh...

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Abstract

The invention belongs to the microfluid manipulation field and relates to a two-dimensional digital microfluid analysis test platform based on acoustic surface wave. The invention comprises four groups of metal comb-like interdigital electrodes with the same sizes and in symmetrical distribution, a graphical hydrophobic coating, a two-dimensional hydrophilic guide rail and a lithium niobate substrate. The invention is characterized in that the bottom is the lithium niobate substrate; the middle of the upper layer is the graphical hydrophobic coating; above the graphical hydrophobic coating are the evenly distributed two-dimensional hydrophilic guide rails; the intersection of the two-dimensional hydrophilic guide rails are a node and the four groups of metal comb-like interdigital electrodes are symmetrically distributed at four sides. The invention not only can resolve the problems of the complicated process of digital microfluid manufacturing and the possibility to enter a dead zone, but also can retain the advantages of less fluid demand of the existing digital microfluid and rapid analysis. The invention can be widely used in chemical and biological detection fields.

Description

Technical field [0001] The invention relates to a device in the technical field of detection, in particular to a two-dimensional digital microfluidic analysis and detection platform based on surface acoustic waves. Background technique [0002] In the past decade or so, as an emerging technology, microfluidics technology has been widely used in biology, medicine, etc. The vast majority of applications are to pump the sample liquid into the channel through the microchannel, and then perform analysis or amplification. Compared with the traditional method, this method requires less liquid volume and fast analysis speed. Recently, researchers have developed a new set of analysis tools called digital microfluidic devices. The digital microfluidic element does not pump the sample liquid into the channel, but uses an electric current to move the droplet on the plane. In typical digital microfluidics, the droplets are located on a set of conductive lining plates. Changing the voltage on ...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G01N33/50
Inventor 李以贵高阳张冠孙健陈少军
Owner SHANGHAI JIAO TONG UNIV
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