Method for the glucose concentration in pulsational blood

A technology of blood sugar concentration and measurement value, applied in the field of blood sugar measurement, can solve the problems of finding a standard calibration method, difficult and so on
CN101557752AInactive Publication Date: 2009-10-14NIRLUS ENG AG
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Patent Information

Authority / Receiving Office
CN Ā· China
Patent Type
Applications(China)
Current Assignee / Owner
NIRLUS ENG AG
Publication Date
2009-10-14
Estimated Expiration
Not applicable Ā· inactive patent

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Abstract

Method for the continuous measurement of the glucose concentration in blood undergoing pulsational flow, with the steps: - determination of a value for the glucose concentration for a first measurement cycle, and - repetition of the determination of this value in subsequent measurement cycles, where there is multiple detection, within each measurement cycle, of the transmittance and / or scattering power of the blood for at least two incident NIR wavelengths, calculation of an indicator value depending on the blood glucose concentration, and ascertaining the blood glucose concentration by comparing the indicator value with a previously determined calibration table, determination of the blood temperature during the detection of the transmittance and / or scattering power, - continuous measurement of the pulse duration of the pulsational blood flow, where the duration of the measurement cycle is arranged to keep in step as integral multiple of the pulse duration, where the first of the at least two NIR wavelengths is selected from the wavelength range 1560-1630 nm, and the second of the at least two NIR wavelengths is selected from the wavelength range 790-815 nm, and the ratio of the transmittance and / or scattering power of the at least two wavelengths is calculated, this ratio serving in relation to the blood temperature as indicator value for reading off the blood glucose concentration from the calibration table.
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Description

technical field

[0001] The invention relates to a method for the contactless measurement of blood glucose by means of NIR (near infrared) spectrometry in flowing pulsating blood, wherein the flowing pulsating blood is in particular first extracted from a living organism and treated, for example, by dialysis It is then infused back into the organism. The invention also relates to a device which is suitable as an additional or integrated part of a dialysis device for monitoring blood glucose levels. The invention can furthermore be used for non-invasive monitoring of blood glucose levels in vivo. Background technique

[0002] Determining the blood glucose level without direct contact with blood, in particular without drawing blood specifically for this purpose, has been the object of intensive medical research and development for more than two decades. Among other things, the main goal is to provide diabetics with a compact, portable measuring device which, ideally at most, ...

Claims

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