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Installation for treating a biological liquid

A biological liquid and equipment technology, applied in the field of biological liquid processing equipment, can solve heavy problems and achieve the effect of simple assembly

Active Publication Date: 2009-12-09
MILLIPORE CORP
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] These treatments are usually carried out in dedicated circuits with stainless steel pipes and other components such as tanks and filter housings, which require operations before and after the treatment and are therefore relatively onerous, especially after use cleaning operation

Method used

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  • Installation for treating a biological liquid
  • Installation for treating a biological liquid
  • Installation for treating a biological liquid

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0051] figure 1 It shows a device for processing biological fluids, including a first trolley 1 and a second trolley 2 in a nested configuration, that is, the second trolley 2 is partially nested in the first trolley 1 . The length of the first trolley 1 is shorter than the length of the second trolley.

[0052] figure 2 The same plant is shown with the two trolleys in a separated configuration, ie the second trolley 2 moved away from the first trolley 1 .

[0053] image 3 The plant is shown comprising the third trolley 3 in nested configuration, ie the third trolley 3 is partially nested (on its left side) in the first trolley 1 . Figure 5 A modification is shown in which the third trolley 3 is longer.

[0054] In another variant not shown, each trolley is designed such that the right side (not the left side) of the second or third trolley is nested in the first trolley.

[0055] First refer to the following Figure 9 A description will be given of a case where a bio...

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PUM

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Abstract

Installation for treating a biological liquid, including a circulation pump, a filter element, a container for collecting treated liquid, a first circuit section connecting a source of said biological liquid to an inlet orifice of said filter element, including a circuit element adapted to cooperate with said circulation pump; a second circuit section, connecting an outlet orifice of said filter element to said treated liquid collecting container; characterized in that said treated liquid collecting container, said first circuit section and said second circuit section are disposable and said installation further includes a first cart carrying said pump and a second cart including a housing for said collecting container, separable from the first cart and adapted to be at least partly nested in said first cart.

Description

technical field [0001] The present invention relates to equipment for processing biological fluids, especially, but not exclusively, for purifying biopharmaceutical fluids to obtain preparations such as monoclonal antibodies, vaccines or recombinant proteins. Background technique [0002] Biopharmaceutical fluids are usually obtained by culturing in bioreactors and must subsequently be purified to achieve desired properties regarding concentration, virus-free, etc. [0003] Purification typically includes clarification to eliminate bioreactor culture residues and viral retention, sometimes followed by dilution filtration and tangential flow filtration (TFF). Other purification treatments include chromatography and sterile filtration (to remove bacteria). [0004] Purification is usually achieved by filtration in a loop leading to a container for collecting the treated liquid. [0005] Various types of liquid-containing containers can be connected to the inlet of the circui...

Claims

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Application Information

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IPC IPC(8): C07K1/34C12M1/12
CPCC12M47/12B01D36/00C12M1/12Y10T436/25375Y10T436/2575
Inventor J-L·伯莱V·比森S·西鲁C·德尔博斯M·赫拉瓦切克F·梅尔斯R·莱茵比格勒J-L·魏森巴赫
Owner MILLIPORE CORP