Method for preparing pharmaceutical composition for treating diseases of urinary system and method for detecting components thereof

A technology for urinary system diseases and detection methods, which is applied in the field of preparation of pharmaceutical compositions for the treatment of urinary system diseases and the detection of its components, and can solve the problems of ineffective treatment of chronic diseases, postoperative recurrence rate of patients suffering, and cost of surgical procedures. For advanced problems, achieve significant ureteral smooth muscle action, diuresis and regulation of ureteral smooth muscle action, and reduce heating time

Active Publication Date: 2010-05-05
JIANGXI HONGXING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The current Western medical treatment for kidney, urinary tract, and bladder stones is surgical stone removal and external instrument vibration crushing stone removal method. The operation cost is high, the patient is painful, and the postoperative recurrence rate is high; although the instrument vibration shock stone removal method is fast. , the course of treatment is short, but the cost of the equipment is high, so it is not suitable for the majority of patients in small towns or rural areas
Traditional Chinese medicine uses various prescriptions for removing stones, and its cost is relatively low, but most folk prescriptions have not passed strict pharmacodynamic experiments and toxicity tests, and the therapeutic effects are also different; for acute pyelonephritis, cystitis, urethritis and sexually transmitted diseases The disease caused by it is currently mostly treated with antibiotic therapy in Western medicine. The therapeutic effect of antibiotics is obvious and fast, but the effect on the treatment of chronic diseases is not significant. Some preparations are used to treat urinary calculi and urinary tract infections, such as Sanjin Tablets (capsules), Qianjintonglin Oral Medicine, Bazheng Mixture, Jisheng Shenqi Pills, and Compound Shiwei Tablets. Diseases such as urinary stones and urinary tract infections have some therapeutic effects, but satisfactory results have not yet been obtained

Method used

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  • Method for preparing pharmaceutical composition for treating diseases of urinary system and method for detecting components thereof
  • Method for preparing pharmaceutical composition for treating diseases of urinary system and method for detecting components thereof
  • Method for preparing pharmaceutical composition for treating diseases of urinary system and method for detecting components thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0058] Guangshen grass 285g Corn silk 188.8g Shiwei 142.5g

[0059] Chicken bone grass 142.5g Poria cocos 142.5g Plantain 103.1g

[0060] Sea golden sand grass 103.1g Imperata 142.5g

[0061] Shiwei chlorogenic acid (C 16 h 18 o 9 ) content 15g

[0062] [Preparation method] Take 120g of Poria cocos and grind them into fine powder for the above eight herbs, and set aside; combine the remaining Poria cocos with the seven herbs of Desmodium stylifolia, corn silk, Shiwei, chicken bone grass, plantain, sea golden sand grass and Imperata rhizome and add water Decoct twice, each time for 3 hours, combine the filtrate, filter, concentrate the filtrate to 1.19-1.20 (90°C) extract, add poria cocos powder, mix well, dry to dry paste, crush into fine powder, and sieve , add appropriate amount of auxiliary materials, mix evenly, granulate, dry, granulate, pack into capsules, and make 1000 capsules.

Embodiment 2

[0064] Guangshen grass 285g Corn silk 188.8g Shiwei 187.5g

[0065] Chicken bone grass 97.5g Poria cocos 142.5g Plantain 103.1g

[0066] Sea golden sand grass 103.1g Imperata 142.5g

[0067] Shiwei chlorogenic acid (C 16 h 18 o 9 ) content 20g

[0068] [Preparation method] Take 120g of Poria cocos and grind them into fine powder for the above eight herbs, and set aside; combine the remaining Poria cocos with the seven herbs of Desmodium stylifolia, corn silk, Shiwei, chicken bone grass, plantain, sea golden sand grass and Imperata rhizome and add water Decoct twice, each time for 3 hours, combine the filtrate, filter, concentrate the filtrate to 1.19-1.20 (90°C) extract, add poria cocos powder, mix well, dry to dry paste, crush into fine powder, and sieve , add appropriate amount of auxiliary materials, mix evenly, granulate, dry, granulate, pack into capsules, and make 1000 capsules.

Embodiment 3

[0070] Desmodium radix 285g Corn silk 188.8g Shiwei 100g

[0071] Chicken bone grass 260g Poria cocos 142.5g Plantain 103.1g

[0072] Sea Gold Sand Grass 103.1g Chine Root 142.5g

[0073] Shiwei chlorogenic acid (C 16 h 18 o 9 ) content 10g

[0074] [Preparation method] Take 120g of Poria cocos and grind them into fine powder for the above eight herbs, and set aside; combine the remaining Poria cocos with the seven herbs of Desmodium stylifolia, corn silk, Shiwei, chicken bone grass, plantain, sea golden sand grass and Imperata rhizome and add water Decoct twice, each time for 3 hours, combine the filtrate, filter, concentrate the filtrate to 1.19-1.20 (90°C) extract, add poria cocos powder, mix well, dry to dry paste, crush into fine powder, and sieve , add appropriate amount of auxiliary materials, mix evenly, granulate, dry, granulate, pack into capsules, and make 1000 capsules.

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Abstract

The invention relates to a method for preparing a pharmaceutical composition for treating diseases of the urinary system and a method for detecting components thereof. The pharmaceutical composition comprises the components of desmodium styracifolium, corn silk, pyrrosia lingua, herba abri, tuckahoe, herba plantaginis, lygodium japonicum and rhizoma imperatae. The method for preparing the pharmaceutical composition comprises the following steps: step 1: dividing the tuckahoe into two parts; step 2: pulverizing the part of the tuckahoe accounting for 80-90% of total weight into fine powder; step 3: decocting the rest tuckahoe and the other seven crude drugs with water; and step 4: adding the fine tuckahoe powder, evenly mixing, drying, pulverizing into fine powder, screening, adding proper amounts of auxiliary materials, evenly mixing, pelletizing, drying, and sorting up the granules. The detecting method comprises the following steps: taking the pharmaceutical composition as the sample solution, and taking a pyrrosia lingua control medicine as the control medicine solution. The preparation technique and the detecting technique of the invention have the advantages of low cost and simple processing, reduce the heating time of the drugs, and are suitable for wide application in clinical treatment.

Description

technical field [0001] The invention relates to a preparation method of a pharmaceutical composition for treating urinary system diseases and a detection method of its components. Background technique [0002] Urinary system diseases are common human diseases. The main symptoms are frequent urination, short red urine, astringent and burning pain in urine, and severe fever, thirst, abdominal pain, waist pain, hematuria, pus discharge, dry or loose stool. Urinary system calculus belongs to the stone stranguria in TCM stranguria syndrome. Traditional Chinese medicine believes that it is formed by damp heat pouring down, turning into fire and scorching yin, tormenting urine, forming sand and gravel, and accumulating waterways. Syndrome differentiation is mainly based on the excess syndrome of dampness-heat and blood stasis in the focus. It is suitable for clearing away heat and promoting dampness, clearing away stranguria and removing stones. Therefore, getting rid of waterwa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P13/00G01N30/90G01N30/36G01N30/02
Inventor 何彦杰
Owner JIANGXI HONGXING PHARMA
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