Nicergoline nasal powder and preparation method thereof

A technology of nicergoline and powder, which is applied in the field of nicergoline nasal powder and its preparation, and achieves the effects of good safety, improved stability and remarkable drug efficacy

Inactive Publication Date: 2010-06-02
HONGYI SCI & TECH CO LTD NANCHANG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although nicergoline tablets, sustained-release granules, capsules, powder injections and injections have been disclosed in the prior art, there is no document disclosing nicergoline nasal powder, especially good stability and nasal administration brain target. Nicergoline nasal powder, easy to use, good compliance, quick onset and high bioavailability

Method used

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  • Nicergoline nasal powder and preparation method thereof
  • Nicergoline nasal powder and preparation method thereof

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Abstract

The invention discloses nicergoline nasal powder and a preparation method thereof. In the nicergoline nasal powder, nicergoline dry powder and carrier dry powder are in a form of capsules or vesicles, the atomized nicergoline is sprayed to the nasal cavity by using a Helioeast dry powder administration device, and a preparation which is in brain targeting administration and treats vascular cretinism is absorbed by the mucous membrane of the nasal cavity. The nicergoline nasal powder contains 1-16 parts by weight of nicergoline dry powder with the particle diameter thereof being 80-250mum and 15-45 parts by weight of carrier dry powder with the particle diameter thereof being 80-250mum.The nicergoline nasal powder features convenient use, good conformability, quick acting of the brain targeting function and high bioavailability.

Description

technical field The invention relates to the field of pharmaceutical preparations, in particular to a nicergoline nasal powder and a preparation method thereof. Background technique Vascular dementia (VD) has been on the rise rapidly in recent years. With the aggravation of urbanization and aging, China's elderly population has exceeded 120 million, and the incidence of geriatric diseases is also increasing year by year. With the increase of residents' income, the requirements of the elderly for the quality of life are also increased. Under this trend, the demand for therapeutic drugs for diseases such as vascular dementia has also increased significantly. VD disease is a disease with declining function and needs long-term medication. With the development of society and the improvement of people's attention to this kind of disease, the demand for therapeutic drugs is constantly increasing. According to the results of the survey of doctors, 8.16% of doctors believe that the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/72A61K31/48A61P25/28A61J3/07
Inventor 刘孝乐朱丹
Owner HONGYI SCI & TECH CO LTD NANCHANG
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