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Infusion method of liquid chromatogram and dual-drive high pressure pump

A liquid chromatography and dual-drive technology, which is applied in pumps, pump devices, machines/engines, etc., can solve problems affecting the stability of liquid chromatography systems, and achieve the effects of efficient and stable infusion methods, reasonable structural design, and convenient maintenance

Inactive Publication Date: 2010-06-09
BEIJING CHUANGXIN TONGHENG SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

For large-flow industrial liquid chromatography, it needs constant flow infusion of high-pressure and ultra-high-pressure infusion, and at the same time, the reciprocating operation of the infusion pump will cause the pulsation of the mobile phase in the infusion pipeline, which will affect the stability of the liquid chromatography system. sex

Method used

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  • Infusion method of liquid chromatogram and dual-drive high pressure pump
  • Infusion method of liquid chromatogram and dual-drive high pressure pump
  • Infusion method of liquid chromatogram and dual-drive high pressure pump

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Embodiment Construction

[0026] The liquid chromatography infusion method can be used in high-pressure or ultra-high pressure liquid chromatography systems. It uses a double-drive high-pressure pump as the infusion device. The double-drive high-pressure pump includes two linear motors driven by a single driver, and the two linear motors are respectively A main pump head and an auxiliary pump head are respectively driven by a transmission mechanism, the main pump head and the auxiliary pump head are connected in series or in parallel, and the main pump head and the auxiliary pump head are mutually compensated to realize pulsation-free infusion. When the series connection is adopted, the main pump head and the auxiliary pump head are connected in series, and the discharge volume of the main pump head is twice that of the auxiliary pump head. The liquid outlet of the main pump head is connected to the liquid inlet of the auxiliary pump head, and the pump cavity of the main pump head is also connected with...

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Abstract

The invention relates to an infusion method of liquid chromatogram and a dual-drive high pressure pump. The infusion method comprises a step of adopting the dual-drive high pressure pump as an infusion device, wherein the dual-drive high pressure pump comprises two linear motors driven by a single driver; the two linear motors drive a main pump head and an auxiliary pump head through a drive mechanism respectively; the main pump head is connected with the auxiliary pump head in series or in parallel; and the main pump head and the auxiliary pump head compensate each other to realize pulse-less infusion. The infusion method is efficient and stable, the main pump head and the auxiliary pump head can realize compensation for each other, and the auxiliary pump head can effectively compensate the reduced flow of the main pump head so as to realize constant high pressure or extra high pressure infusion. The dual-drive high pressure pump has a reasonable structure design, is convenient to maintain, and can realize the constant delivery of high pressure or extra high pressure mobile phases for a long term.

Description

technical field [0001] The invention belongs to the preparation liquid chromatography technology, and in particular relates to an infusion method and a double-drive high-pressure pump applied to a high-performance liquid chromatography system and an ultra-high pressure liquid chromatography system. Background technique [0002] The high-pressure infusion pump is an important unit instrument in the high-performance liquid chromatography system HPLC, and the ultra-high pressure pump is an indispensable infusion unit in the ultra-high pressure liquid chromatography system UPLC. The basic requirement of the ultra-high pressure pump is to maintain constant flow and constant pressure under the working pressure of 40 to 101MPa to ensure the accuracy and stability of the flow. For large-flow industrial liquid chromatography, it needs constant flow infusion of high-pressure and ultra-high-pressure infusion, and at the same time, the reciprocating operation of the infusion pump will c...

Claims

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Application Information

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IPC IPC(8): B01D15/08F04B23/06F04B17/03
Inventor 崔万臣沈志刚
Owner BEIJING CHUANGXIN TONGHENG SCI & TECH
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