Extraction method of ophiopogon root, ginseng and shiandra and preparation thereof
The technology of Schisandra chinensis and ginseng is applied in the field of preparation of Qi and Fumai for treating cardiovascular diseases and its preparation, which can solve the problems of low extraction rate, high cost, complicated production process and the like, and achieves high extraction rate, low cost and high curative effect. Effect
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Embodiment 1
[0059] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:
[0060] Add 30% ethanol in an amount 4 times the amount of the crude drug, adjust the pH to 9, and extract under reflux for 1 hour each time, and the product obtained is a combined extract.
[0061] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:
[0062] Remove the medicinal materials and use 80% ethanol to reflux extract once, each time for 30 minutes, after filtration, add water to the filter residue and decoct for extraction twice, each time for 1 hour, the extract is ultrafiltered with an ultrafiltration membrane with a cut-off molecular weight of 30,000, and the effluent is collected , concentrated under reduced pressure, the product obtained is a single extract,
[0063] The combination of the above combined extract and single extract is the extract of the present invention.
Embodiment 2
[0065] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:
[0066] Add 10 times the amount of crude drug and 50% ethanol, adjust the pH to 14, reflux extraction, 3 hours each time, extract 3 times, and the product obtained is a composite extract.
[0067] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:
[0068] Remove the medicinal materials and use 95% ethanol to reflux extract 3 times, each time for 1 hour, after filtering, add water to the filter residue and decoct and extract 3 times, each time 2 hours, the extract is ultrafiltered with an ultrafiltration membrane with a cut-off molecular weight of 100,000, and the effluent is collected , concentrated under reduced pressure, the product obtained is a single extract,
[0069] The combination of the above combined extract and single extract is the extract of the present invention.
Embodiment 3
[0071] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:
[0072] Add 40% ethanol 6 times the amount of crude drug, adjust the pH to 12, reflux extraction, 2 hours each time, extract 2 times, and the product obtained is a composite extract.
[0073] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:
[0074] Remove the medicinal materials and use 90% ethanol to reflux and extract twice, each time for 1 hour. After filtration, add water to the filter residue and decoct for extraction 3 times, each time for 2 hours. , concentrated under reduced pressure, the product obtained is a single extract,
[0075] The combination of the above combined extract and single extract is the extract of the present invention.
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