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Extraction method of ophiopogon root, ginseng and shiandra and preparation thereof

The technology of Schisandra chinensis and ginseng is applied in the field of preparation of Qi and Fumai for treating cardiovascular diseases and its preparation, which can solve the problems of low extraction rate, high cost, complicated production process and the like, and achieves high extraction rate, low cost and high curative effect. Effect

Inactive Publication Date: 2013-03-13
TIANJIN TASLY ZHIJIAO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0015] In the prior art, the production process is complicated, the cost is high, and the problems of low extraction rate have not been overcome

Method used

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  • Extraction method of ophiopogon root, ginseng and shiandra and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:

[0060] Add 30% ethanol in an amount 4 times the amount of the crude drug, adjust the pH to 9, and extract under reflux for 1 hour each time, and the product obtained is a combined extract.

[0061] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0062] Remove the medicinal materials and use 80% ethanol to reflux extract once, each time for 30 minutes, after filtration, add water to the filter residue and decoct for extraction twice, each time for 1 hour, the extract is ultrafiltered with an ultrafiltration membrane with a cut-off molecular weight of 30,000, and the effluent is collected , concentrated under reduced pressure, the product obtained is a single extract,

[0063] The combination of the above combined extract and single extract is the extract of the present invention.

Embodiment 2

[0065] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:

[0066] Add 10 times the amount of crude drug and 50% ethanol, adjust the pH to 14, reflux extraction, 3 hours each time, extract 3 times, and the product obtained is a composite extract.

[0067] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0068] Remove the medicinal materials and use 95% ethanol to reflux extract 3 times, each time for 1 hour, after filtering, add water to the filter residue and decoct and extract 3 times, each time 2 hours, the extract is ultrafiltered with an ultrafiltration membrane with a cut-off molecular weight of 100,000, and the effluent is collected , concentrated under reduced pressure, the product obtained is a single extract,

[0069] The combination of the above combined extract and single extract is the extract of the present invention.

Embodiment 3

[0071] (1) Combined extraction of ginseng and schisandra, the extraction steps are as follows:

[0072] Add 40% ethanol 6 times the amount of crude drug, adjust the pH to 12, reflux extraction, 2 hours each time, extract 2 times, and the product obtained is a composite extract.

[0073] (2) Ophiopogon japonicus is extracted separately, and the extraction steps are as follows:

[0074] Remove the medicinal materials and use 90% ethanol to reflux and extract twice, each time for 1 hour. After filtration, add water to the filter residue and decoct for extraction 3 times, each time for 2 hours. , concentrated under reduced pressure, the product obtained is a single extract,

[0075] The combination of the above combined extract and single extract is the extract of the present invention.

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Abstract

The invention relates to a Chinese traditional medicine extraction method and a pharmaceutical preparation thereof, in particular to a preparation for treating cardiovascular diseases, tonifying qi and calming pulse and a preparation method thereof. The preparation is prepared from ginseng, ophiopogon root and shiandra.

Description

Technical field: [0001] The invention relates to a method for extracting traditional Chinese medicine and its pharmaceutical preparation, in particular to a preparation for nourishing qi and rejuvenating pulse for treating cardiovascular diseases and a preparation method thereof. Background technique: [0002] Ginseng is the root of Araliaceae Panax ginseng C.A.Mey. Its medicinal properties are sweet, slightly bitter, flat, and belong to the lung, spleen, and heart channels; Application: Syndrome of deficiency of vitality, syndrome of deficiency of lung, spleen, heart and kidney qi, syndrome of febrile disease, syndrome of qi deficiency, fluid wound, thirst and diabetes. Its chemical composition includes a variety of ginsenosides, volatile oils, amino acids, trace elements and organic acids, sugars, vitamins, etc. [0003] Ophiopogon japonicus, also known as japonica and book daicao, is a perennial evergreen herb of the genus genus Liliaceae. The fibrous roots are relativ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P5/00A61P9/02A61P9/10
Inventor 郑永锋王未东范立君杨悦武叶正良周大峥彭可让孙建强
Owner TIANJIN TASLY ZHIJIAO PHARMA
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