Swelling reducing and pain easing gel and preparation method thereof

A technology for reducing swelling, relieving pain, and gel preparation, which is applied in the directions of non-central analgesics, pharmaceutical formulations, and non-active ingredients medical preparations, etc., and can solve the problems of volatile solvent, complicated preparation process, turbidity or precipitation, etc.

Inactive Publication Date: 2010-06-30
CHONGQING PHARMA RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] The anti-tumor and analgesic tincture currently used clinically is a liquid preparation, which has certain defects. For example, the glass container of the tincture is easily damaged during transportation and carrying. ...

Method used

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  • Swelling reducing and pain easing gel and preparation method thereof
  • Swelling reducing and pain easing gel and preparation method thereof
  • Swelling reducing and pain easing gel and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] Prescription: CMC-Na 225g, swelling and pain relief tincture 6000g, purified water 1275g

[0082] Preparation:

[0083] Weigh CMC-Na, add swelling and analgesic tincture solution, stir evenly, continuously stir and slowly add purified water to the specified amount, make a gel, make 7500g, pack it separately, and get it.

Embodiment 2

[0085] Prescription: CMC-Na 250g, glycerin 500g, PEG400 300g, swelling and pain relief tincture 6000g, purified water 1050g

[0086] Preparation:

[0087] Weigh CMC-Na, add it to the mixture of glycerin and PEG400, grind to make the CMC-Na fully dispersed, then add swelling and pain-relieving tincture solution, stir evenly, finally add purified water to the specified amount, stir to form a gel, Made into 8100g, divided into packages, and you get it.

Embodiment 3

[0089] Prescription: 45g of CMC-Na, 125g of ethanol, 5300ml of percolating liquid of medicinal material for reducing swelling and relieving pain tincture, 55g of camphor, 55g of menthol, proper amount of purified water

[0090] Prescription of swelling and pain relieving tincture medicinal percolation solution:

[0091] Woody 47g, Fangfeng 47g, Nepeta 47g, Asarum 47g, Wujiapi 47g, Guizhi 47g, Achyranthes bidentata 47g, Chuanxiong 47g, Xu Changqing 47g, Angelica dahurica 70g, Curcuma 47g, Red Eucommia 70g, Daluo umbrella 100g, small Luosan 70g, Liangmianzhen 100g, Huangteng 95g, Gardenia 100g, Sanleng 70g, Agarwood 32.5g

[0092] Preparation:

[0093] a) Preparation of swelling and analgesic tincture medicinal material infiltration liquid: take the nineteen medicinal materials in the prescription and grind them into coarse powder, according to the percolation method under the item of liquid extract and extract in "Chinese Pharmacopoeia" 2005 edition, use 53% Use ethanol as a ...

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Abstract

The invention relates to swelling reducing and pain easing gel and preparation method thereof. The gel mainly contains swelling reducing and pain easing tincture liquid medicine, gel substrate and other pharmaceutical adjuvant and has the characteristics of small dosage of the adjuvant and good stability. The gel acts locally, has the functions of stimulating blood circulation and causing the muscles and joints to relax, reducing swelling and easing pain, and is used for curing injuries from falls, rheumatism, unknown swelling and toxin, and parotitis swelling. The gel has the advantages of long dwell time, durable effect, simple formulation process, low production cost and strong operability in industrial production.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine preparations, and relates to a traditional Chinese medicine gel preparation, in particular to a swelling and pain-relieving tincture prepared through process improvement into a swelling-relieving gel. Background technique [0002] Gel (Gel) refers to a homogeneous, suspension or emulsion-type latex thick liquid or semi-solid preparation made of a drug and an excipient capable of forming a gel. Gels can be divided into systemic gels and topical gels. At present, most topical gels are skin gels. According to different substrates, gels are divided into water-based gels and oily gels. The main substrates of water-based gels are generally carbomer, cellulose derivatives, alginate, tragacanth, pectin, gelatin, xanthan, etc. Glue, agar, non-cellulosic polysaccharides such as chitin, ethylene polymer, acrylic resin, polyvinyl alcohol and polycarboxyethylene, etc.; the main matrix of ...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K9/00A61K47/38A61P29/00A61K31/125
Inventor 任运强刘泽荣邓杰聂进张涛樊斌
Owner CHONGQING PHARMA RES INST
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