Veterinary synergic enrofloxacin injection and preparation method thereof

Abstract

The invention relates to the field of veterinary medicament, in particular to a veterinary synergic enrofloxacin injection. Based on the total amount of 100mL, the injection comprises the following components by weight: 5 to 10g of enrofloxacin, 10 to 12g of sodium salicylate, water extract of 20 to 40g of isatis root, 1 to 2g of trimethoprim, 20 to 40g of polyethylene glycol 400, 0.1 to 1g of sodium hydroxide, and the balance injection water, wherein the mass ratio of the enrofloxacin to the trimethoprim is 5 to 1; and the mass ratio of the trimethoprim to the polyethylene glycol 400 is 1:20. The injection has high stability and freezing resistance, and excellent effect in antibiosis and virus resistance, can effectively reduce generation of drug tolerance, and is particularly suitable for serious mixed infection of bacterium, virus and mycoplasma for animals. The invention also relates to a method for preparing the injection, and has the advantages of convenient operation, low cost and the like.

Description

Veterinary synergistic enrofloxacin injection and preparation method thereof technical field The invention relates to the field of veterinary drugs, in particular to a veterinary synergistic enrofloxacin injection and a preparation method of the injection. Background technique Enrofloxacin is a third-generation fluoroquinolone drug specially used for animals. It has significant curative effect on infections caused by various bacteria and is suitable for digestion caused by sensitive bacteria and mycoplasma in cattle, pigs, poultry, dogs, cats and aquatic animals. System, respiratory system, urinary system and various infectious diseases of skin and soft tissues, mainly used for infections caused by Pasteurella, Haemophilus, Escherichia coli, Salmonella, Streptococcus, Mycoplasma, etc. With the improvement of people's living standards in recent years, the demand for meat products has increased, and large-scale farms have increased year by year. However, the breeding enviro...

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Problems solved by technology

In view of this, one of the objectives of the present invention is to provide a synergistic enrofloxacin injection for veterinary use, which can not only solve the difficulties of high-concentration enrofloxacin injection preparation difficulty, poor product stability and freeze resistance, Moreover, its antibacterial and antiviral effects can be greatly enhanced, and the generation of drug resistance can be effectively reduced; the second purpose is to provide a preparation method of the veterinary synergistic enrofloxacin injection, which is easy to operate and low in cost, suitable for industrial mass production

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