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Salvianolic acid B phospholipid composition and preparation method thereof

A technology of salvianolic acid and composition, applied in the field of salvianolic acid B phospholipid composition and its preparation, can solve the problems of shortening the course of treatment for hepatitis

Inactive Publication Date: 2010-11-24
BEIJING SUNHO PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although soybean phospholipid is not an antidote against the pathogenic source of hepatitis, it has a certain effect on shortening the course of treatment and preventing the formation of liver cirrhosis

Method used

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  • Salvianolic acid B phospholipid composition and preparation method thereof

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Abstract

The invention a salvianolic acid B phospholipid composition, which consists of salvianolic acid B and soyabean lecithin, wherein the weight ratio of the salvianolic acid B to the soyabean lecithin is 1:0.5-2. The invention also discloses a preparation method of the salvianolic acid B phospholipid composition, which has the advantages of simple operation and low cost. The salvianolic acid B phospholipid composition prepared by utilizing the method of the invention can improve the bioavailability of the salvianolic acid B obviously, has the effect of protecting liver and normalizing gallbladder and is used for treating hepatic fibrosis and liver cirrhosis.

Description

A kind of salvianolic acid B phospholipid composition and preparation method thereof technical field The invention relates to the technical field of medicine, in particular to a salvianolic acid B phospholipid composition and a preparation method thereof. Background technique Liver fibrosis is a common pathological change of chronic hepatitis caused by many different etiologies, and its further development will lead to liver cirrhosis. Therefore, the prevention and treatment of liver fibrosis has important clinical significance. The pathological feature of liver fibrosis is the abnormal proliferation and excessive deposition of extracellular matrix (ECM) in the liver. ) is the most important cytokine that promotes HSC activation. After HSC is activated by various factors, the production of ECM (especially collagen) in the cells increases significantly, and at the same time, the expression of matrix metalloproteinase (matrixmet-alloproteinase, MMP) inhibitor increases, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/685A61K31/343A61P1/16
Inventor 张树祥范宇宁
Owner BEIJING SUNHO PHARMA