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Composition for preventing and treating joint soft tissue injury and complications thereof

A soft tissue injury and composition technology, which is applied in the field of compositions for the prevention and treatment of joint soft tissue injury and concurrent inflammation, can solve the problems of short maintenance time, influence on training and performance improvement, and cover up, so as to accelerate repair and generation, and relieve joint pain , reducing the effect of PGE2

Active Publication Date: 2011-03-09
BEIJING COMPETITOR SPORTS SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Chronic damage to the connective tissue around the joints can also cause jumping knee, tennis elbow, shoulder and elbow inflammation, etc., and even affect normal training and performance improvement in severe cases
[0003] At present, there are many kinds of products on the market for the prevention and treatment of joint soft tissue lesions, which can be summarized into two categories: one is non-steroidal anti-inflammatory drugs, such as ibuprofen, diclofenac sodium, etc., which have anti-inflammatory and analgesic effects. The metabolism in the body is fast, once the metabolism is completed, the pain will start again immediately, and the maintenance time is very short. More importantly, the pain relief only controls the superficial phenomenon of the disease, but conceals the essence of the disease that is still developing
The other is traditional Chinese medicine therapy, through the treatment methods of expelling wind and cold, relieving spasm and dredging collaterals, promoting blood circulation and removing stasis, so that stiff joint muscles can be relaxed and muscle spasms can be relieved, thereby achieving the effects of dredging meridians, reducing swelling and relieving pain, but At present, it has not been found that traditional Chinese medicine can repair articular cartilage, or have an effect on articular cartilage cells, and human physiology and anatomy have proved that there are no blood vessels in articular cartilage. Whether the theory of "activating blood circulation and removing stasis" often mentioned in traditional Chinese medicine can work on articular cartilage remains to be seen. pending further research

Method used

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  • Composition for preventing and treating joint soft tissue injury and complications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The preparation of composition capsule of the present invention:

[0037] The raw materials bone collagen, sodium hyaluronate, mangosteen extract, pomegranate extract and vitamin C were selected and sieved respectively, and the materials under the 40-mesh sieve were used to prepare the preparation.

[0038] Weigh the screened raw materials: 500g of bone collagen, 400g of sodium hyaluronate, 300g of mangosteen extract, 200g of pomegranate extract, 50g of vitamin C, 10g of magnesium stearate, stir well, pour into the capsule filling mold, pour Capsules were packed, polished and subpackaged to obtain 3000 capsules.

Embodiment 2

[0040] The preparation of composition granule of the present invention:

[0041] The raw materials bone collagen, sodium hyaluronate, mangosteen extract, pomegranate extract and vitamin C were sieved respectively, and the materials under the 80-mesh sieve were used to prepare the preparation.

[0042] Weigh and screen raw materials respectively: 2000g of bone collagen, 100g of sodium hyaluronate, 1200g of mangosteen extract, 50g of pomegranate extract, 200g of vitamin C, 1000g of sucrose powder, stir well and evenly, and use a concentration of 50% (vol%) Ethanol is used as a binder to make soft materials. The above soft materials are passed through a 14-mesh sieve oscillating granulator to make granules, and the granules are placed in a multifunctional boiling dryer, and boiled and dried at 50°C for about 40 minutes to control the water content of the granules. 5%, then granulate and sub-package to obtain 1000 bags of granules.

Embodiment 3

[0044] The preparation of composition tablet of the present invention:

[0045] The raw materials bone collagen, sodium hyaluronate, mangosteen extract, pomegranate extract and vitamin C were sieved respectively, and the materials under the 80-mesh sieve were used to prepare the preparation.

[0046] Weigh and screen raw materials: 1500g of bone collagen, 150g of sodium hyaluronate, 800g of mangosteen extract, 75g of pomegranate extract, 150g of vitamin C, 600g of lactose, and 200g of microcrystalline cellulose, stir well and use a concentration of 50% (vol%) of ethanol is used as a binding agent to make a soft material, and the above-mentioned soft material is passed through a 14-mesh sieve oscillating granulator to make granules, and the granules are placed in a multifunctional boiling dryer, and boiled and dried for about 40 minutes at 50 ° C. The water content of the granules is controlled to 5%, sized, and then 0.5% of the total weight of raw materials is added to the gra...

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Abstract

The invention relates to a composition for preventing and treating joint soft tissue injury and complications thereof. A complex formulation, which comprises bone collagen, sodium hyaluronate, mangosteen extract, pomegranate extract and vitamin C in specific proportions, is prepared. The composition has an anti-inflammatory effect, since the generation of PGE2 is reduced by lowering the activity of COX2. Meanwhile, the composition accelerates the restoration and generation of cartilage tissue and joint fluid and lowers the degree of joint inflammation.

Description

technical field [0001] The invention relates to a health care product, in particular to a composition for preventing and treating joint soft tissue damage and concurrent inflammation. Background technique [0002] For any competitive sport, athlete's injury is the biggest obstacle in training and competition. Sports trauma is one of the main problems that plague athletes. It often affects training plans and performance improvement due to injuries, and even shortens sports life. According to relevant survey data, sports injuries are characterized by more chronic injuries and less acute injuries and serious injuries. Most of the chronic injuries are caused by local fatigue and the gradual accumulation of many micro-damages. After long-term and high-intensity training, athletes often experience symptoms such as joint soreness, pain, and mild swelling. Some people also experience tenderness in tendons and ligaments. The reason is that the athletes' joints often have to carry ...

Claims

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Application Information

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IPC IPC(8): A61K38/39A61P19/02A61P19/04A61P29/00A61K31/728A61K31/375
Inventor 白厚增焦颖杨则宜朱连君宋贵林
Owner BEIJING COMPETITOR SPORTS SCI & TECH
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