Chinese medicinal double-layer patch for treating oral ulcer and preparation method thereof
A technology of oral ulcer and traditional Chinese medicine, which is applied in the field of traditional Chinese medicine oral ulcer double-layer patch and its preparation, can solve problems such as low anticipation and allergen ulcer, and achieve the effect of alleviating pain, reducing discomfort and strong adhesion
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Embodiment 1
[0040] 1. 8 grams of mint, 15 grams of honeysuckle, 5 grams of licorice, 10 grams of Chinese gall, decocted 3 times in water, 2 hours each time, concentrated the water extract to a specific gravity of 1.2-1.4, and centrifuged at a high speed; 2. Centrifuged liquid or concentrated Dried to obtain the crude extract; 3. Macroporous resin, eluted with water, concentrated after decolorization of the eluent, precipitated with 95% ethanol, placed in the refrigerator, filtered, vacuum-dried the filter cake, crushed and sieved or spray-dried to obtain off-white Extract in fine powder form.
Embodiment 2
[0042] Reflux 12 grams of mint, 20 grams of honeysuckle, 10 grams of licorice, and 15 grams of Gallnut, reflux with 75% ethanol, extract 3 times, concentrate the filtrate into an extract, add water to make the extract into a suspension, and wash with water through macroporous resin D301 After decolorization, the eluate is concentrated, precipitated with 95% ethanol, placed in the refrigerator, filtered, and the filter cake is vacuum-dried, pulverized, sieved or spray-dried to obtain an off-white fine powder extract.
Embodiment 3
[0044] 10 grams of mint, 150 grams of honeysuckle, 8 grams of licorice, 15 grams of gallnut, 10 grams of mint, 150 grams of honeysuckle, 8 grams of licorice, 15 grams of gall, reflux with 95% ethanol, extract twice, concentrate the filtrate into an extract, add water Make the extract into a suspension, elute with macroporous resin D301, water, decolorize the eluent, concentrate, precipitate with 95% ethanol, place in the refrigerator, filter, vacuum dry the filter cake, crush and sieve or spray dry to obtain the White fine powder extract.
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