Chinese medicine composition for treating hypertension and preparation method thereof

A composition and high blood pressure technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of curative effect discount, backward preparation process, single taste of medicine, etc.

Inactive Publication Date: 2012-12-19
北京凯瑞创新医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the single flavor of the prescription and the relatively backward preparation technology of the above-mentioned drugs, the clinical curative effect is greatly reduced

Method used

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  • Chinese medicine composition for treating hypertension and preparation method thereof
  • Chinese medicine composition for treating hypertension and preparation method thereof
  • Chinese medicine composition for treating hypertension and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0055] Prescription: Gastrodia elata 900g, Uncaria 900g, Moutan bark 300g, Scutellaria baicalensis 300g, mother of pearl 675g, Eucommia 675g

[0056] Preparation method: Take Moutan cortex, add 10 times the amount of water to distill, receive 6 times the amount of distillate, refrigerate, crystallize, wrap with β-cyclodextrin, and dry; the medicinal product after distillation of Gastrodia elata, Eucommia, mother-of-pearl and Moutan bark Combine the slag, add 8 times the amount of water to decoct twice, each time for 1.5 hours, filter, combine the filtrate and the distilled water of Moutan bark, concentrate under reduced pressure to 60°C, measure the relative density to 1.08-1.10, add ethanol to make the alcohol-containing The amount reaches 40%, overnight, filter, and the filtrate recovers ethanol to 60°C to measure the water liquid with a relative density of about 1.08-1.10, add saturated lime milk to adjust the pH to 11.0, let it stand for 1 hour, and adjust the pH to 5.0 wit...

Embodiment 2

[0058] Prescription: Gastrodia elata 1200g, Uncaria 900g, Moutan bark 300g, Scutellaria baicalensis 300g, mother of pearl 900g, Eucommia 900g

[0059] Preparation method: Take Moutan cortex, add 10 times the amount of water to distill, receive 6 times the amount of distillate, refrigerate, crystallize, wrap with β-cyclodextrin, and dry; the medicinal product after distillation of Gastrodia elata, Eucommia, mother-of-pearl and Moutan bark Combine the slag, add 8 times the amount of water to decoct twice, each time for 1.5 hours, filter, combine the filtrate and the distilled water of Moutan bark, concentrate under reduced pressure to 60°C, measure the relative density to 1.08-1.10, add ethanol to make the alcohol-containing The amount reaches 40%, overnight, filter, and the filtrate recovers ethanol to 60°C to measure the water liquid with a relative density of about 1.08-1.10, add saturated lime milk to adjust the pH to 11.0, let it stand for 1 hour, and adjust the pH to 5.0 wi...

Embodiment 3

[0061] Prescription: Gastrodia elata 500g, Uncaria 500g, Moutan bark 600g, Scutellaria baicalensis 600g, mother of pearl 1000g, Eucommia 300g

[0062] Preparation method: Take Moutan cortex, add 12 times the amount of water to distill, receive 8 times the amount of distillate, refrigerate, crystallize, wrap with β-cyclodextrin, and dry; the medicinal product after distillation of Gastrodia elata, Eucommia, mother of pearl and Moutan bark Combine the slag, add 6 times the amount of water to decoct 3 times, each time for 1 hour, filter, combine the filtrate and the distilled water of Moutan bark, concentrate under reduced pressure to 60°C, measure the relative density to 1.08-1.10, add ethanol to make the alcohol-containing The amount reaches 50%, overnight, filter, and recover ethanol from the filtrate to 60°C to measure the water liquid with a relative density of about 1.08-1.10, add saturated lime milk to adjust the pH to 11.0, let it stand for 1 hour, and adjust the pH to 5.0...

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Abstract

The invention discloses a Chinese medicine composition for treating hypertension and a preparation method thereof, belonging to the field of Chinese medicines. The Chinese medicine composition comprises bulk pharmaceutical chemicals of gastrodia tuer, uncaria rhynchophylla, the bark of eucommia and the like. The bulk pharmaceutical chemicals are distilled with steam, decocted with water, extracted with alcohol and the like respectively according to different characteristics for extracting effective components and prepared into a capsule, a tablet, a granular formulation, powder and a pill. The Chinese medicine composition has the functions of calming liver wind and calming and reducing blood pressure and is mainly used for treating the liver-yang hyperactivity type hypertension.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating hypertension and a preparation method thereof. It belongs to the field of traditional Chinese medicine. Background technique [0002] Hypertension is a common and frequently-occurring disease. The prevalence of hypertension in my country is 11.88%, with an average annual increase rate of more than 3 million, and the number of patients with hypertension reaches 110 million. According to the results of the National Hypertension Sampling Survey, the prevalence of hypertension increases with age, and it increases significantly after the age of 45. It is only 4% in the 25-34 age group, and increases by 1% in the 35-44 age group. After that, the prevalence rate will increase by about 10% every 10 years. The urban prevalence rate is obviously higher than that in the rural areas, and the prevalence rate is similar betw...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8988A61P9/12A61K35/56A61K35/618
Inventor 孙志强李凌军
Owner 北京凯瑞创新医药科技有限公司
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