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Composition of disinfectant and preparation method thereof

A disinfectant and mixture technology, applied in the field of disinfectant and its preparation, can solve the problems of affecting bactericidal power, low bactericidal concentration, corrosion of poultry and livestock, etc., and achieve the effect of prolonging the service life, simple preparation method and low irritation

Active Publication Date: 2011-05-25
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Quaternary ammonium salt has the advantages of low bactericidal concentration, non-toxic, non-corrosive, non-irritating, etc., but its disinfection range is narrow, and it is ineffective against mycoplasma and spores
The joint use of aldehydes and quaternary ammonium salts can play a complementary role. For example, patent CN101161070A prepared a disinfectant by compounding double-chain quaternary ammonium salts with o-phthalaldehyde, and patent CN 101579330A combined glutaraldehyde, single-chain quaternary ammonium salts, Although the disinfectants prepared jointly with chain quaternary ammonium salts have improved the shortcomings of low bactericidal effect caused by the use of aldehydes or quaternary ammonium salts alone, but due to the corrosiveness of aldehydes themselves, the service life of livestock and poultry breeding equipment will be reduced. shorten
In addition, the patent CN 1476761A discloses a liquid disinfectant composed of quaternary ammonium salts, biguanides, and aldehydes, but the above-mentioned disinfectant is aimed at the "Disinfection Technical Specifications" document that meets the health requirements of hospitals, and the types of harmful microorganisms in livestock and poultry farms Great changes have taken place, and a large amount of feces are processed every day, resulting in poor air quality and strong odor in the living environment, which brings inconvenience to breeding management
Only changing the content and ratio of quaternary ammonium salts, biguanides, and aldehydes of the disinfectant will often affect the bactericidal power of multi-component disinfectants due to changes in their physical and chemical properties.
Moreover, changes in the content of quaternary ammonium salts, biguanides, and aldehydes may lead to changes in the stability of disinfectants, corrosion of poultry and livestock, resulting in shortened service life of farming equipment, and even some toxic effects on farmers or poultry and livestock

Method used

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  • Composition of disinfectant and preparation method thereof
  • Composition of disinfectant and preparation method thereof
  • Composition of disinfectant and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] 1. disinfectant of the present invention and preparation method thereof

[0041] Glutaraldehyde 5% (W / V)

[0042]Chlorhexidine Acetate 0.6% (W / V)

[0043] Dodecyldimethylbenzylammonium bromide 8% (W / V)

[0044] Fatty alcohol polyoxyethylene ether 2% (W / V)

[0045] Turpentine 2% (W / V)

[0046] Terpineol 2% (W / V)

[0047] Disodium EDTA 0.01% (W / V)

[0048] Sodium metaphosphate 1% (W / V)

[0049] Purified water to full volume

[0050] Preparation steps:

[0051] 1) Take 5L of purified water, add 500g of glutaraldehyde, and stir evenly;

[0052] 2) Add 800 g of dodecyl dimethyl benzyl ammonium bromide and 200 g of fatty alcohol polyoxyethylene ether to step 1), and stir evenly;

[0053] 3) Add 200 g of turpentine, 200 g of terpineol, and 60 g of chlorhexidine acetate to step 2), stir evenly, and adjust the pH to 5.0 with glacial acetic acid;

[0054] 4) Add 1 g of disodium ethylenediamine tetraacetate and 100 g of sodium metaphosphate to step 3), add purified water...

Embodiment 2

[0092] 1. disinfectant of the present invention and preparation method thereof

[0093] Phthalaldehyde 2% (W / V)

[0094] Chlorhexidine Acetate 1% (W / V)

[0095] Lauryl Dimethyl Benzyl Ammonium Chloride 15% (W / V)

[0096] Fatty alcohol polyoxyethylene ether 3% (W / V)

[0097] Turpentine 2% (W / V)

[0098] Terpineol 2% (W / V)

[0099] EDTA 0.05% (W / V)

[0100] Potassium metaphosphate 0.05% (W / V)

[0101] Sodium metaphosphate 0.5% (W / V)

[0102] Purified water to full volume

[0103] Preparation steps:

[0104] 1) Take 4.5L of purified water, add 200g of o-phthalaldehyde, and stir evenly;

[0105] 2) Add 1500 g of dodecyl dimethyl benzyl ammonium chloride and 300 g of fatty alcohol polyoxyethylene ether into step 1), and stir evenly;

[0106] 3) Add 200 g of turpentine, 200 g of terpineol, and 100 g of chlorhexidine acetate to step 2), stir evenly, and adjust the pH to 5.5 with glacial acetic acid;

[0107] 4) Add 5 g of ethylenediamine tetraacetic acid, 5 g of potassium ...

Embodiment 3

[0129] 1. disinfectant of the present invention and preparation method thereof

[0130] Glutaraldehyde 15% (W / V)

[0131] Polyhexamethyleneguanidine 0.6% (W / V)

[0132] Didodecyldimethylammonium Chloride 5% (W / V)

[0133] Fatty alcohol polyoxyethylene ether 1% (W / V)

[0134] Turpentine 3% (W / V)

[0135] Terpineol 3% (W / V)

[0136] Disodium EDTA 0.01% (W / V)

[0137] Sodium metaphosphate 1% (W / V)

[0138] Purified water to full volume

[0139] Preparation

[0140] 1) Take 4L of purified water, add 1500g of glutaraldehyde, and stir evenly;

[0141] 2) Add 500 g of didodecyldimethyl ammonium chloride and 100 g of fatty alcohol polyoxyethylene ether into step 1), and stir evenly;

[0142] 3) Add 300 g of turpentine, 300 g of terpineol, and 60 g of polyhexamethyleneguanidine to step 2), stir evenly, and adjust the pH to 4.5 with glacial acetic acid;

[0143] 4) Add 1 g of disodium ethylenediamine tetraacetate, 100 g of sodium metaphosphate, and purified water to 10 L in st...

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Abstract

The invention relates to a composition of a disinfectant and a preparation method thereof, and belongs to the field of medicines for veterinary use. The liquid disinfectant comprises 2 to 15 percent (W / V) of aldehydes, 0.6 to 1 percent (W / V) of biguanides, 0 to 15 percent (W / V) of quaternary ammonium salt and the balance of carrier, and the total percentage of the materials is 100 percent. The preparation method comprises the following steps of: 1) adding 2 to 15 percent (W / V) of aldehydes into purified water in an amount which is 40 to 70 percent of the total volume, and stirring uniformly; 2) adding 0 to 15 percent W / V of quaternary ammonium salt and 0 to 3 percent (W / V) of fatty alcohol-polyoxyethylene ether into the mixture in the step 1), and stirring uniformly; 3) adding 1 to 3 percent (W / V) of turpentine, 1 to 3 percent (W / V) of terpineol and 0.6 to 1 percent (W / V) of biguanides into the mixture in the step 2), stirring uniformly, and regulating the pH value to between 3.0 and 7.0 by using glacial acetic acid; 4) adding 0.01 to 0.1 percent (W / V) of chelant and 0.05 to 1 percent (W / V) of corrosion inhibitor into the mixture in the step 3), adding the purified water to the total amount, stirring uniformly, filtering and filling to obtain the composition. The disinfectant has the advantages of high efficiency, no irritation, small corrosivity and the like, is used for disinfection of livestock and poultry environment, equipment and the like, and has a wide market prospect and a high market value.

Description

technical field [0001] The invention relates to a disinfectant and a preparation method thereof, in particular to a disinfectant composition suitable for disinfection of livestock and poultry breeding places and a preparation method thereof. Background technique [0002] With the development of modern intensive farming, closed and highly intensive feeding conditions make livestock and poultry more and more threatened by pathogenic microorganisms. Although a lot of money is invested in vaccines and drugs, it is still impossible to avoid the impact of diseases The harm of animals, these diseases also threaten the health of human beings while they exist. The most fundamental factor causing animal diseases is pathogenic microorganisms, especially livestock and poultry feces contain a large number of pathogenic microorganisms, parasite eggs, and breeding mosquitoes and flies, which will increase the types of pathogens and the amount of bacteria in the environment, resulting in hu...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A01N47/44A01N35/04A01N35/02A01N33/12A01N25/00A01P1/00A01N31/04
Inventor 刘兴金张许科张晓会
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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