Traditional Chinese medicine preparation for treating chronic hepatitis b and preparation method thereof
A technology of chronic hepatitis B and traditional Chinese medicine preparations, which is applied in the direction of medical formulas, medical preparations containing active ingredients, pill delivery, etc. It can solve the problems of high production costs, poor curative effect, and large toxic and side effects of western medicines, and achieve enhanced The immune function of the body, the recovery of immune function to normal, and the effect of promoting liver cell proliferation
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preparation example Construction
[0053] The preparation method of the tablet of the present invention comprises: taking Angelica sinensis 1000g, Hedyotis diffusa 1000g, Astragalus 1000g, Houttuynia cordata 1000g, Bupleurum 1000g, Nasturtium 1000g, Scutellaria baicalensis 1000g, Forsythia 1000g, Radix isatidis 1000g, Prunella vulgaris 1000g, Honeysuckle 1000g, Schisandra 1000g, Poria cocos 1000g, Atractylodes macrocephala 1000g, Shouwu 1000g, Ligustrum lucidum 1000g, Eclipta 1000g, Salvia miltiorrhiza 1000g, Baishao 1000g, capillary wormwood 1000g, Qingdai 1000g, Scutellaria barbata 1000g, Phellodendron 1000g, Attach 1000g, licorice 1000g, and white moss bark 1000g. The components are mixed according to the ratio, put into a pulverizer and pulverized into fine powder, and the fine powder is sieved and put into an acid and alkali resistant dipping pot. After ~20 days, press and filter the impregnated liquid and dregs, separate and take the filtrate, heat and concentrate until it becomes a paste, mix it with star...
experiment example 2
[0065] Experimental example 2: long-term toxicity test data
[0066] 1. Experimental method
[0067] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe 24 hours later, each group of guinea pigs is respectively coated with 0.2, 0.4 and 0.8ml of the Chinese medicine preparation capsule for oral administration of the present invention, respectively containing crude drug 92, 184 and 368mg, and another group is coated with solvent 0.8ml twice a day, continuously After 30 days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.
[0068] 2. Results
[0069] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of guinea...
experiment example 3
[0070] Experimental example 3: Cumulative toxicity test:
[0071] Chinese medicine preparation oral administration capsule of the present invention is to mice by 7.69,19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention The hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of the rats were not significantly affected. After 3 weeks of drug withdrawal, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.
[0072] Pharmacological experiment description:
[0073] 1. Objects and me...
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