Traditional Chinese medicine preparation for treating chronic hepatitis b and preparation method thereof

A technology of chronic hepatitis B and traditional Chinese medicine preparations, which is applied in the direction of medical formulas, medical preparations containing active ingredients, pill delivery, etc. It can solve the problems of high production costs, poor curative effect, and large toxic and side effects of western medicines, and achieve enhanced The immune function of the body, the recovery of immune function to normal, and the effect of promoting liver cell proliferation

Inactive Publication Date: 2011-06-01
陈玲
View PDF0 Cites 18 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The technical problem to be solved by the present invention is to need a kind of low price, less toxic and side effects, significant curative effect, long-term taking Chinese medicine preparation to treat patients with chronic hepatitis B; most of the medicines for treating chronic hepatitis B in the prior art are The use of western medicine has large toxic a

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine preparation for treating chronic hepatitis b and preparation method thereof
  • Traditional Chinese medicine preparation for treating chronic hepatitis b and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0053] The preparation method of the tablet of the present invention comprises: taking Angelica sinensis 1000g, Hedyotis diffusa 1000g, Astragalus 1000g, Houttuynia cordata 1000g, Bupleurum 1000g, Nasturtium 1000g, Scutellaria baicalensis 1000g, Forsythia 1000g, Radix isatidis 1000g, Prunella vulgaris 1000g, Honeysuckle 1000g, Schisandra 1000g, Poria cocos 1000g, Atractylodes macrocephala 1000g, Shouwu 1000g, Ligustrum lucidum 1000g, Eclipta 1000g, Salvia miltiorrhiza 1000g, Baishao 1000g, capillary wormwood 1000g, Qingdai 1000g, Scutellaria barbata 1000g, Phellodendron 1000g, Attach 1000g, licorice 1000g, and white moss bark 1000g. The components are mixed according to the ratio, put into a pulverizer and pulverized into fine powder, and the fine powder is sieved and put into an acid and alkali resistant dipping pot. After ~20 days, press and filter the impregnated liquid and dregs, separate and take the filtrate, heat and concentrate until it becomes a paste, mix it with star...

experiment example 2

[0065] Experimental example 2: long-term toxicity test data

[0066] 1. Experimental method

[0067] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe 24 hours later, each group of guinea pigs is respectively coated with 0.2, 0.4 and 0.8ml of the Chinese medicine preparation capsule for oral administration of the present invention, respectively containing crude drug 92, 184 and 368mg, and another group is coated with solvent 0.8ml twice a day, continuously After 30 days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.

[0068] 2. Results

[0069] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​guinea...

experiment example 3

[0070] Experimental example 3: Cumulative toxicity test:

[0071] Chinese medicine preparation oral administration capsule of the present invention is to mice by 7.69,19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine preparation of the present invention The hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of the rats were not significantly affected. After 3 weeks of drug withdrawal, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

[0072] Pharmacological experiment description:

[0073] 1. Objects and me...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

The invention relates to a traditional Chinese medicine preparation for treating chronic hepatitis b, which comprises the following raw medicines: angelica sinensis, oldenlandia diffusa, astragali, houttuynia, radix bupleuri, tropaeolum, baical skullcap, forsythia, isatis, self-heal, honeysuckle, magnolia vine fruit, tuckahoe, white atractylodes rhizome, prepared fleece-flower root, glossy privet fruit, yerbadetajo, root of red rooted salvia, white peony root, oriental wormwood, natural indigo, barbat skullcap, phellodendron bark, rhizoma cyperi, liquorice and cortex dictamni radicis. The traditional Chinese medicine preparation has the efficacies of soothing the liver, regulating the flow of qi, relieving the depressed liver, promoting blood circulation, removing blood stasis, invigorating qi, restoring qi, strengthening the body resistance, consolidating the constitution, and tonifying the liver and kidney. The traditional Chinese medicine preparation has the following beneficial effects of: 1, clearing away heat and toxic material, promoting urination and elimination of toxicant, removing heat from the liver, gall and liver, promoting blood circulation, removing blood stasis, strengthening the spleen and removing dampness by diuresis; 2, protecting liver, reducing enzyme, removing toxin, restoring the liver function to normal, and thoroughly removing virus; and 3, nourishing after birth, enhancing the body immunologic function, and promoting hepatocyte proliferation. All medicines have synergistic effects to restore the body immunologic function to normal and achieve the purposes of removing virus and promoting recovery.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals and a preparation method thereof, in particular to a traditional Chinese medicine preparation for treating chronic hepatitis B and a preparation method thereof. Background technique [0002] Viral hepatitis B is a worldwide disease caused by the hepatitis B virus (HBV). The incidence rate is high in developing countries. According to statistics, there are more than 280 million asymptomatic hepatitis B virus carriers (HBsAg carriers) in the world, and my country accounts for about 130 million. Most of them are asymptomatic, and 1 / 3 of them have clinical manifestations of liver damage. At present, there are 30 million hepatitis B patients in our country. Hepatitis B is characterized by slow onset, and subclinical and chronic types are more common. Anicteric HBsAg persistently positive patients tend to become chronic. The disease is mainly tra...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
IPC IPC(8): A61K36/8905A61K9/20A61K9/48A61P1/16A61P31/20
Inventor 陈玲崔守凤郭瑶
Owner 陈玲
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap