Porous bone cement

Abstract

The invention provides porous bone cement. The porous bone cement comprises powder and aqua, wherein the aqua is water or inorganic salt aqueous solution; the powder comprises (a) more than two bone substitute materials of different grain sizes, (b) calcium sulfate and (c) absorbable molecules, wherein the bone substitute materials are independently selected from a group consisting of calcium phosphate, polymer and metal or salts thereof, and a restrictive condition of the bone substitute materials is that at least one bone substitute material is the calcium phosphate; the absorbable molecules can be dissolved in organisms of the aqua; and the absorbing or decomposing speed of the absorbable molecules in the organisms is higher than the absorbing or decomposing speed of the calcium sulfate. The porous bone cement can be applied to treatment of dental and bone defects, aesthetic operation and the like; and structural strength and porosity of cured bone cement can be simultaneously considered by mixing the more than two bone substitute materials of different grain sizes and materials which are absorbed or decomposed in two organisms at different speeds.

Description

technical field [0001] The present invention relates to a novel porous bone cement which can be used in the treatment of dental and skeletal defects and cosmetic plastic surgery. Background technique [0002] Bone cement materials are mainly used in the treatment of bone defects in organisms, and can support the affected part after filling to avoid secondary injuries. In general, bone cement consists of a powder composed of bone substitute material and a water agent for mixing, which is mixed before use to make it fluid. The nature of the fluid is relatively easy to achieve tight packing, and must be cured in a short time after implantation to prevent damage from body fluids. Of course, the structural strength after curing must also be sufficient to support the affected part in order to avoid secondary injuries. [0003] Bone cement materials rarely emphasize the importance of porosity due to the need to maintain structural strength. The bone cement material with holes ha...

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Problems solved by technology

However, neither of the above mentioned much ink on the particle size of the bone substitute material

If bone substitute materials with smaller particles are used, such as figure 1 As shown, due to the small gap between the particles, the material structure after curing is tight. When the material is dissolved, it will be affected by the structure too tight to form obvious holes, and it is impossible for cells to grow smoothly in the holes.

Conversely, if bone substitute materials with larger particles are used, such as figure 2 As shown, due to the large particle gap, the solidified structure is relatively loose. Although holes can be formed for cell growth when the substance dissolves, it will cause a large decrease in mechanical strength or even structural disintegration.

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