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A kind of salaminophen dry suspension and preparation method thereof

A technology of dry suspension and salivamol, which is applied in the field of pharmacy and medicine using salivamol as raw material, which can solve the problems of insoluble bile pigment stones, achieve low incidence of adverse reactions, low-cost production, and expand application range effect

Inactive Publication Date: 2011-11-30
扬州市三药制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, this product cannot dissolve pigment stones, mixed stones and X-ray opaque stones

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0027] Salsaminophen 125g

[0028] Sodium Carboxymethyl Cellulose·Microcrystalline Cellulose 400g

[0029] Dextrin 200g

[0030] Sucrose 500g

[0031] 5% povidone K30 ethanol solution about 200ml

[0032] Fragrance 5ml

example 2

[0034] Salsaminophen 150g

[0035] Sodium Carboxymethyl Cellulose·Microcrystalline Cellulose 400g

[0036] Dextrin 200g

[0037] Sucrose 500g

[0038] Stevioside 2.5g

[0039] 5% povidone K30 ethanol solution about 200ml

[0040] Fragrance 5ml

[0041] Note: The sodium carboxymethylcellulose·microcrystalline cellulose used in the present invention is an imported auxiliary material, produced by Asahi Kasel Corporation, and its specification is RC-A-591NF.

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Abstract

A dry suspension of salivamol and a preparation method thereof relate to the technical field of medicine. First, salivamol, a flavoring suspending agent, and a filler are respectively pulverized and passed through a 100-120 mesh sieve; then salivamol, Filler, suspending agent, flavoring agent and binder solution are mixed and granulated, then dried at 55±5°C; then packaged. The process of the invention is simple and reasonable, convenient for production, beneficial to low energy consumption, low-cost production, and good product stability. The invention adopts a new type of auxiliary material, sodium carboxymethyl cellulose and microcrystalline cellulose. After the product is added with water, it can quickly form a uniformly distributed suspension. The product has a sweet smell. After taking it, the human body hardly absorbs it. High concentration, low incidence of adverse reactions, and mild. The invention expands the application range of salaminol, and makes up for the defect of poor compliance of patients taking solid preparations.

Description

Technical field [0001] The invention relates to the technical field of medicine, in particular to the technical field of pharmacy using sulfanol as a raw material. Background technique [0002] Salsaminophen is a choleretic. This product promotes bile secretion and can increase bile secretion several times without changing its composition. Its effect is similar to that of dehydrocholic acid. It can increase hepatic blood flow, improve liver function, and increase the water content in bile significantly. Strong dehydrocholic acid. This product has atropine-like antispasmodic effect, can relax the sphincter of Oddi, and is suitable for cholecystitis, cholecystitis, gallstones and post-gallbladder surgery syndrome. In addition, it has the effect of lowering blood cholesterol. [0003] After oral administration, sulfanol is mainly absorbed in the small intestine in an alkaline environment. After being metabolized, this product is excreted with feces. Long-term use can increase the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K31/609A61K47/38A61P1/16
Inventor 徐园祝瑞章
Owner 扬州市三药制药有限公司
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