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Chinese medicinal composition for treating superficial mycosis infection and medicinal composition thereof

A technology of fungal infection and composition, applied in the field of traditional Chinese medicine composition and pharmaceutical composition for treating superficial fungal infection

Inactive Publication Date: 2012-12-26
NAVY MEDICINE RES INST OF PLA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The patents that can be retrieved in the application of Dioscorea dioica are mainly used for antidiarrheal in children (CN 1415327), treatment of enteritis and dysentery (CN 1524564), treatment of hemorrhoids (CN101428109, CN101361884 and CN1814130) or tumor treatment (CN 1736457), etc. patent, there is no patent report on the use of yam yam for the treatment of fungal skin infections

Method used

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  • Chinese medicinal composition for treating superficial mycosis infection and medicinal composition thereof
  • Chinese medicinal composition for treating superficial mycosis infection and medicinal composition thereof
  • Chinese medicinal composition for treating superficial mycosis infection and medicinal composition thereof

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preparation example Construction

[0054] The preparation method of the traditional Chinese medicine powder for treating skin mycosis is as follows: take the raw materials of the medicinal components, dry them at 60-80°C for 30-40 minutes, pulverize them respectively, sieve them, and blend them according to the weight ratio of the medicinal components to prepare Chinese medicine powder.

[0055] The preparation method of the traditional Chinese medicine lotion for treating skin mycosis is as follows: according to the weight of 1:5-10, take the effective raw materials and water, first decoct the yam and flavescens for 10-25 minutes, then add alum and boil for 10-25 minutes. After 25 minutes, filter and cool to make a traditional Chinese medicine lotion.

[0056] The method of use of this preparation is: externally applied to the affected area once a day in the morning and evening, 2-3 weeks as a course of treatment. For damp and erosive skin infections, foot odor, foot rot and other diseases, Chinese medicine p...

Embodiment 1

[0059] The preparation of embodiment 1 Chinese medicine composition and extract thereof

[0060] Table 1

[0061] Buttercup Sophora flavescens alum Powder 1 15 20 8 Chinese herbal lotion 1 22 23 15 Chinese herbal lotion 2 25 17 12 Extract 1 9 10 6 extract 2 23 18 10

[0062] According to the ratio listed in Table 1, prepare as follows:

[0063] Powder preparation method: take the effective raw materials (dried yam tuber needs to be crushed), dry at 60-80°C for 35 minutes, pulverize them respectively, sieve, pair and mix according to the weight ratio of the above-mentioned effective components, Make traditional Chinese medicine powder.

[0064] Chinese medicine lotion and preparation method thereof are carried out in the following manner:

[0065] Taking medicinal raw materials and water according to a weight ratio of 1:5-10, decocting yam, flavescens and alum step by step for 10-25 mi...

Embodiment 2

[0071] Embodiment 2: antifungal experiment

[0072] Methods: Sabouraud medium was prepared and filled into Erlenmeyer flasks, and sterilized under high pressure. Get respectively according to prepared Chinese medicine lotion stoste and 10, 60, 120 times of dilutions and clotrimazole medicinal solution stoste and 10 times, 60 times, 120 times of dilutions respectively 1ml of injecting sterilized petri dish with aseptic method In each dose group, 5 plates (10 cm in diameter of the plate) were poured into Sabouraud culture to inoculate 4 kinds of superficial fungi (Trichophyton rubrum, Trichophyton gypsum, Trichophyton flocculus, about 0.5 mm in diameter) Bacterial group), cultivated at 37°C for 1 week, observe the growth state of the colony and whether there is growth of miscellaneous bacteria, measure the diameter of the colony (mm) and compare it with the control plate. Results The traditional Chinese medicine lotion has a good antifungal effect, and its effect is better than...

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Abstract

The invention relates to the technical field of traditional Chinese medicines, in particular to a Chinese medicinal composition for treating superficial mycosis infection and a medicinal composition thereof, and discloses a Chinese medicinal composition for treating superficial mycosis infection. The Chinese medicinal composition is characterized by comprising the following single traditional Chinese medicines in parts by weight: 15-25 parts of dye yam, 17-23 parts of lightyellow sophora root and 8-15 parts of alum. Compared with the prior art, the Chinese medicinal composition has the remarkable advantages of innovative formula, safety, no toxic or side effect, and wide application range.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating superficial fungal infection and a pharmaceutical composition thereof. Background technique [0002] Superficial fungal infection is one of the common clinical skin diseases. It belongs to damp-heat invasion syndrome in traditional Chinese medicine. It has symptoms such as erythema, papules, blisters, exudation, erosion, desquamation, itching, pain, etc., which seriously hinder people's normal life and work; And the disease incidence rate is high, protracted. At present, the drugs for the treatment of superficial fungal infections of the skin are mostly two categories: one is the drug with western medicine as the main component, and the symptomatic treatment is mostly with chemical drugs and antibiotics, such as Zuguangsan, 1% calamine lotion, dermatitis flat Ointment, dacryline ointment, ketoconazole o...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8945A61P15/00A61P17/00A61P17/06A61P31/04A61P31/10A61P33/02A61K33/06
Inventor 王庆敏雷呈祥王洵沈俊万辉王庆蓉
Owner NAVY MEDICINE RES INST OF PLA
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